Evidence map›Paper›PMID 36703757›Full record

ArticleFrontiers in pharmacology2022

The mechanism of oxymatrine on atopic dermatitis in mice based on SOCS1/JAK-STAT3 pathway.

Xianwei Han, Tianming Ma, Qiang Wang, Chunlin Jin, Yusheng Han, Guijun Liu, Hao Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Xianwei HanDepartment of Dermatology, The Seventh People's Hospital of Shenyang, Shenyang, China.
Tianming MaThe Second Hospital of Heilongjiang University of Chinese Medicine, Harbin, China.
Qiang WangDepartment of Dermatology, The Seventh People's Hospital of Shenyang, Shenyang, China.
Chunlin JinDepartment of Dermatology, The Seventh People's Hospital of Shenyang, Shenyang, China.
Yusheng HanHeilongjiang University of Chinese Medicine, Harbin, China.
Guijun LiuHeilongjiang University of Chinese Medicine, Harbin, China.
Hao LiShenzhen University General Hospital, Shenzhen, China.
Heilongjiang University of Chinese Medicine · CNSeventh People's Hospital of Shanghai · CNShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Based on the suppressor of cytokine signaling 1 (SOCS1)/Janus kinase (JAK)/signal transducer and activator of transcription 3 (STAT3) pathway, the mechanism of oxymatrine in the treatment of atopic dermatitis (AD) was preliminarily explored in this study. C57BL/6 mice were induced to establish AD model by smearing carbotriol (MC903) on their back. The AD mice were randomly divided into model group, oxymatrine groups with three dosages (25, 50 and 100 mg/kg), (

Indexed as

atopic dermatitisJAK-STAT3janus kinaseoxymatrineSOCS1

Identifiers

PMID36703757
PMCPMC9872557
OpenAlexW4315433265

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.