Evidence map›Paper›PMID 36703642›Full record

ArticleFrontiers in neurology2022

Evident lower blood levels of multiple nutritional compounds and highly prevalent malnutrition in sub-acute stroke patients with or without dysphagia.

Nick van Wijk, Bettina Studer, Claudia A van den Berg, Dina Ripken, Mirian Lansink, Mario Siebler, Tobias Schmidt-Wilcke

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07353658 (The Effect of Intermittent Versus Continuous Enteral Feeding on Outcomes in Severe Stroke), which is not on this map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07353658 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Effect of Intermittent Versus Continuous Enteral Feeding on Outcomes in Severe Stroke: An Exploratory Study

TypeinterventionalSponsorXijing HospitalRan2026 to 2026Enrolled60ConditionsSevere Stroke, Enteral NutritionArmsIntermittent Enteral Feeding, Continuous Enteral Feeding
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Nick van WijkDanone Nutricia Research, Utrecht, Netherlands.
Bettina StuderSt. Mauritius Therapieklinik, Meerbusch, Germany.
Claudia A van den BergDanone Nutricia Research, Utrecht, Netherlands.
Dina RipkenDanone Nutricia Research, Utrecht, Netherlands.
Mirian LansinkDanone Nutricia Research, Utrecht, Netherlands.
Mario SieblerNeurologie und Neurorehabilitation, Fachklinik Rhein Ruhr, Essen, Germany.
Tobias Schmidt-WilckeSt. Mauritius Therapieklinik, Meerbusch, Germany.
Danone Nutricia Research (Netherlands)St. Mauritius Therapieklinik · DEDanone (Netherlands) · NLNutricia Research (Netherlands) · NLRuhrlandklinik · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Malnutrition is prevalent after stroke, particularly if post-stroke oropharyngeal dysphagia (OD) reduces nutritional intake. To further understand stroke-related malnutrition, a thorough nutritional assessment was performed in ischemic stroke patients with or without OD during sub-acute inpatient rehabilitation. Methods: In this exploratory, observational, cross-sectional, multi-center study in Germany (NTR6802), ischemic stroke patients with ( Results: More than half of the stroke patients displayed (risk of) malnutrition, with higher prevalence in patient with OD Discussion: This study shows that malnutrition is highly prevalent in sub-acute stroke patients during rehabilitation. Even though patients with OD were more likely to be malnourished, blood levels of specific nutritional compounds were similarly lower in stroke patients with or without OD compared to healthy reference subjects. Furthermore, subgroup analysis showed similarly lower blood levels of specific nutritional compounds in patients that are normal nourished

Indexed as

blood levelsischemic strokemalnutrition (MeSH)nutritional intakenutritional status (source: MeSH NLM)oropharyngeal dysphagiarehabilitationvitamins

Identifiers

PMID36703642
PMCPMC9872791
OpenAlexW4315432689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.