Evidence map›Paper›PMID 36703580›Full record

SynthesisCurrent neuropharmacology2023

A Systematic Review on Traumatic Brain Injury Pathophysiology and Role of Herbal Medicines in its Management.

Kaushal Arora, Vishal Vats, Nalin Kaushik, Deepanshu Sindhawani, Vaishali Saini, Divy Mohan Arora, Yogesh Kumar, Etash Vashisht, Govind Singh, Prabhakar Kumar Verma

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Current neuropharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Kaushal AroraDepartment of Pharmaceutical Sciences Maharshi Dayanand University, Rohtak, Haryana, 124001, India.
Vishal VatsDepartment of Pharmaceutical Sciences Maharshi Dayanand University, Rohtak, Haryana, 124001, India.
Nalin KaushikDepartment of Pharmaceutical Sciences, Chaudhary Bansi Lal University, Bhiwani, Haryana, 127031, India.
Deepanshu SindhawaniDepartment of Pharmaceutical Sciences Maharshi Dayanand University, Rohtak, Haryana, 124001, India.
Vaishali SainiDepartment of Pharmaceutical Sciences Maharshi Dayanand University, Rohtak, Haryana, 124001, India.
Divy Mohan AroraDepartment of Pharmaceutical Sciences Guru Jambheshwar University of Science & Technology, Hisar, Haryana, 125001, India.
Yogesh KumarSat Priya College of Pharmacy, Rohtak, Haryana, 124001, India.
Etash VashishtDepartment of Pharmaceutical Sciences Maharshi Dayanand University, Rohtak, Haryana, 124001, India.
Govind SinghDepartment of Pharmaceutical Sciences Maharshi Dayanand University, Rohtak, Haryana, 124001, India.
Prabhakar Kumar VermaDepartment of Pharmaceutical Sciences Maharshi Dayanand University, Rohtak, Haryana, 124001, India.
Maharshi Dayanand University · INChaudhary Devi Lal University · INGuru Jambheshwar University of Science and Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraumatic brain injury (TBI) is a worldwide problem. Almost about sixtynine million people sustain TBI each year all over the world. Repetitive TBI linked with increased risk of neurodegenerative disorder such as Parkinson, Alzheimer, traumatic encephalopathy. TBI is characterized by primary and secondary injury and exerts a severe impact on cognitive, behavioral, psychological and other health problem. There were various proposed mechanism to understand complex pathophysiology of TBI but still there is a need to explore more about TBI pathophysiology. There are drugs present for the treatment of TBI in the market but there is still need of more drugs to develop for better and effective treatment of TBI, because no single drug is available which reduces the further progression of this injury.

objectiveThe main aim and objective of structuring this manuscript is to design, develop and gather detailed data regarding about the pathophysiology of TBI and role of medicinal plants in its treatment.

methodThis study is a systematic review conducted between January 1995 to June 2021 in which a consultation of scientific articles from indexed periodicals was carried out in Science Direct, United States National Library of Medicine (Pubmed), Google Scholar, Elsvier, Springer and Bentham.

resultsA total of 54 studies were analyzed, on the basis of literature survey in the research area of TBI.

conclusionRecent studies have shown the potential of medicinal plants and their chemical constituents against TBI therefore, this review targets the detailed information about the pathophysiology of TBI and role of medicinal plants in its treatment.

Indexed as

Brain Injuries, TraumaticDementiaNeurodegenerative DiseasesPlants, MedicinalHumansPlant ExtractsPlant Extractsglucose metabolisminflammationmedicinal herbal plantsneurodegenerative disorderoxidative stresspathophysiologyTraumatic brain injury

Identifiers

PMID36703580
PMCPMC10616914
OpenAlexW4318200061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.