Evidence map›Paper›PMID 36703471›Full record

ArticleCommunications chemistry2020

Hyperpolarized water through dissolution dynamic nuclear polarization with UV-generated radicals.

Arthur C Pinon, Andrea Capozzi, Jan Henrik Ardenkjær-Larsen

Open access · goldAbstract read
In one paragraph

Article in Communications chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Hyperpolarized NMR Reveals Low-Populated Folding Intermediates in DNA.Journal of the American Chemical Society · 2025
    Article
  6. Stable electron-irradiated [1-Science advances · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Cryogenic and Dissolution DNP NMR on γ-Irradiated Organic Molecules.Journal of the American Chemical Society · 2024
    Article
  11. Review
  12. Article
  13. Dynamic Nuclear Polarization Using Electron Spin Cluster.The journal of physical chemistry letters · 2024
    Article
  14. The journal of physical chemistry letters · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Arthur C Pinon *Center for Hyperpolarization in Magnetic Resonance, Department of Health Technology, Technical University of Denmark, Building 349, 2800, Kgs Lyngby, Denmark.
Andrea Capozzi *Center for Hyperpolarization in Magnetic Resonance, Department of Health Technology, Technical University of Denmark, Building 349, 2800, Kgs Lyngby, Denmark.
Jan Henrik Ardenkjær-LarsenCenter for Hyperpolarization in Magnetic Resonance, Department of Health Technology, Technical University of Denmark, Building 349, 2800, Kgs Lyngby, Denmark. jhar@dtu.dk.ORCID http://orcid.org/0000-0001-6167-6926
Technical University of Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, hyperpolarization of water protons via dissolution Dynamic Nuclear Polarization (dDNP) has attracted increasing interest in the magnetic resonance community. Hyperpolarized water may provide an alternative to Gd-based contrast agents for angiographic and perfusion Magnetic Resonance Imaging (MRI) examinations, and it may report on chemical and biochemical reactions and proton exchange while perfoming Nuclear Magnetic Resonance (NMR) investigations. However, hyperpolarizing water protons is challenging. The main reason is the presence of radicals, required to create the hyperpolarized nuclear spin state. Indeed, the radicals will also be the main source of relaxation during the dissolution and transfer to the NMR or MRI system. In this work, we report water magnetizations otherwise requiring a field of 10,000 T at room temperature on a sample of pure water, by employing dDNP via UV-generated, labile radicals. We demonstrate the potential of our methodology by acquiring a

Identifiers

PMID36703471
PMCPMC9814647
OpenAlexW3023037815

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.