Evidence map›Paper›PMID 36703459›Full record

ReviewCommunications chemistry2020

Single electron transfer-based peptide/protein bioconjugations driven by biocompatible energy input.

Yue Weng, Chunlan Song, Chien-Wei Chiang, Aiwen Lei

Abstract readReview
In one paragraph

Review in Communications chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Chemical Conjugation to Less Targeted Proteinogenic Amino Acids.Chembiochem : a European journal of chemical biology · 2022
    Review
  7. Review
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yue WengMinistry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecule & School of Chemistry and Chemical Engineering, Hubei University, 430062, Wuhan, Hubei, China.
Chunlan SongCollege of Chemistry and Molecular Sciences, Wuhan University, 430072, Wuhan, Hubei, China.
Chien-Wei ChiangCollege of Chemistry and Molecular Sciences, Wuhan University, 430072, Wuhan, Hubei, China. cwchiang@whu.edu.cn.
Aiwen LeiCollege of Chemistry and Molecular Sciences, Wuhan University, 430072, Wuhan, Hubei, China. aiwenlei@whu.edu.cn.ORCID http://orcid.org/0000-0001-8417-3061

Funding

National Natural Science Foundation of China (National Science Foundation of China) 21520102003National Natural Science Foundation of China (National Science Foundation of China) 21701127National Natural Science Foundation of China (National Science Foundation of China) 21702150
6 · The paper itself

Abstract

Bioconjugation reactions play a central facilitating role in engendering modified peptides and proteins. Early progress in this area was inhibited by challenges such as the limited range of substrates and the relatively poor biocompatibility of bioconjugation reagents. However, the recent developments in visible-light induced photoredox catalysis and electrochemical catalysis reactions have permitted significant novel reactivities to be developed in the field of synthetic and bioconjugation chemistry. This perspective describes recent advances in the use of biocompatible energy input for the modification of peptides and proteins mainly, via the single electron transfer (SET) process, as well as key future developments in this area.

Identifiers

PMID36703459
PMCPMC9814624

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.