ArticleCommunications chemistry2020
Mineral-mediated carbohydrate synthesis by mechanical forces in a primordial geochemical setting.
Article in Communications chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Article
- The Formose Reaction with SOLife (Basel, Switzerland) · 2026Article
- Mechanochemical Deep Impact: Delivering Sustainable Synthesis and Hydrogen Innovation.ChemSusChem · 2026Article
- Abiotic sugar enantiomers in the CI carbonaceous chondrite Orgueil.Nature communications · 2026Article
- Detection of a four-carbon sugar in interstellar space.Nature astronomy · 2026Article
- Formaldehyde and its surrogates as a C1 platform for defossilised modern societies.Chemical Society reviews · 2025Review
- Environmental History is Transferred via Minerals Altering Formose Reaction Pathways.Angewandte Chemie (International ed. in English) · 2025Article
- Multilayered substructures of a non-enzymatic chemical reaction network for synthesizing sugars.Communications chemistry · 2025Article
- Reciprocating thermochemical mediator of pre-biotic polymer decomposition on mineral surfaces.Journal of the Royal Society, Interface · 2025Article
- The second wave of formose research.BBA advances · 2025Article
- Sulfur Analogs of the Core Formose Cycle: A Free Energy Map.Life (Basel, Switzerland) · 2024Article
- Exploring the Core Formose Cycle: Catalysis and Competition.Life (Basel, Switzerland) · 2024Article
- Article
- Exploring Chemical Space UsingACS central science · 2024Article
- Construction of an autocatalytic reaction cycle in neutral medium for synthesis of life-sustaining sugars.Chemical science · 2023Article
- The protometabolic nature of prebiotic chemistry.Chemical Society reviews · 2023Review
- Towards a prebiotic chemoton - nucleotide precursor synthesis driven by the autocatalytic formose reaction.Chemical science · 2023Article
- Metal-Organic Frameworks as Formose Reaction Catalysts with Enhanced Selectivity.Molecules (Basel, Switzerland) · 2023Article
- On the origin of life: an RNA-focused synthesis and narrative.RNA (New York, N.Y.) · 2023Article
- Serpentinization-Associated Mineral Catalysis of the Protometabolic Formose System.Life (Basel, Switzerland) · 2023Article
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Authors and funding
4 authors.
Funding
Abstract
The formation of carbohydrates represents an essential step to provide building blocks and a source of chemical energy in several models for the emergence of life. Formaldehyde, glycolaldehyde and a basic catalyst are the initial components forming a variety of sugar molecules in the cascade-type multi-step formose reaction. While numerous side reactions and even deterioration can be observed in aqueous media, selective prebiotic sugar formation is feasible in solid-state, mechanochemical reactions and might have occurred in early geochemistry. However, the precise role of different basic catalysts and the influence of the atmospheric conditions in the solid-state formose reaction remain unknown. Here we show, that in a primordial scenario the mechanochemical formose reaction is capable to form monosaccharides with a broad variety of mineral classes as catalysts with only minute amounts of side products such as lactic acid or methanol, independent of the atmospheric conditions. The results give insight into recent findings of formose sugars on meteorites and offer a water-free and robust pathway for monosaccharides independent of the external conditions both for the early Earth or an extra-terrestrial setting.
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