Evidence map›Paper›PMID 36703272›Full record

SynthesisInternational journal of geriatric psychiatry2023

The impact of caregiving on quality of life in Parkinson's disease: A systematic review.

Kate Perepezko, Jared T Hinkle, Elana J Forbes, Gregory M Pontone, Kelly A Mills, Joseph J Gallo

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in International journal of geriatric psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Kate PerepezkoJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0003-3762-563X
Jared T HinkleJohns Hopkins School of Medicine, Baltimore, Maryland, USA.
Elana J ForbesMonash University, Clayton, Victoria, Australia.
Gregory M PontoneJohns Hopkins School of Medicine, Baltimore, Maryland, USA.
Kelly A MillsJohns Hopkins School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-4302-1501
Joseph J GalloJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Johns Hopkins University · USMonash University · AU

Funding

Medical Scientist Training ProgramT32GM136577 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ANDREA L COX · 2020 to 2026
$13.4M
Astrocyte NLRP3 inflammasome activation in Parkinson's diseaseF30AG067643 · NIA · JOHNS HOPKINS UNIVERSITY · PI HINKLE, JARED · 2020 to 2022
$153k
Evaluating the role of the caregiver in the quality of life of people with Parkinson?s disease: opportunities for interventionF31AG066316 · NIA · JOHNS HOPKINS UNIVERSITY · PI PEREPEZKO, KATE M · 2019 to 2021
$91k
NIA NIH HHS F30 AG067643NIA NIH HHS F31 AG066316NIGMS NIH HHS T32 GM136577
6 · The paper itself

Abstract

objectiveParkinson's disease (PD) is a progressive neurodegenerative disease that can reduce quality of life (QOL). Previous research has explored patient specific factors that influence QOL; but understanding external factors that may also affect patient QOL, such as caregiver characteristics, can provide additional intervention targets that may improve QOL for both the person with PD and their caregiver.

methodsWe conducted a systematic review of existing literature on caregiver factors that are related to QOL for the person with PD. We developed a tailored search strategy in six databases and performed a screening procedure according to PRISMA guidelines. We synthesized findings from articles that met inclusion criteria using a narrative approach and identified themes categorizing caregiver factors associated with PD QOL.

resultsWe found 32 full-text articles that fulfilled the inclusion criteria and passed the quality appraisal. Seven themes were identified, including: (1) burden, (2) strain, (3) QOL and satisfaction, (4) demographic factors, (5) psychological factors, (6) relationship factors, and (7) caregiver input.

conclusionsOur review presents critical insights into the role of the caregiver in the QOL of a person with PD. Findings reveal several targets for intervention to improve QOL in this population.

Indexed as

Neurodegenerative DiseasesParkinson DiseaseCaregiversDepressionHumansQuality of LifeburdencaregiverParkinson's diseasequality of lifestrain

Identifiers

PMID36703272
PMCPMC10214089
OpenAlexW4315782116

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.