ArticleArthritis research & therapy2023
Association of physical activity with physical function and quality of life in people with hip and knee osteoarthritis: longitudinal analysis of a population-based cohort.
Article in Arthritis research & therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- The Impact of Exercise Prescription Variables on Intervention Outcomes in Musculoskeletal Pain: An Umbrella Review of Systematic Reviews.Sports medicine (Auckland, N.Z.) · 2024Pooled it
- Does Long-Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?Arthritis care & research · 2026Trial
- Effects of a Digitally Supported Physical Activity Intervention in Knee Osteoarthritis: A Pilot Randomized Controlled Trial.Musculoskeletal care · 2025Trial
- Understanding Chronic Hip Pain Through the ICF Framework: Implications for Assessment, Diagnosis, and Management.Orthopaedic surgery · 2026Review
- A Qualitative Exploration of the Multidimensional Influences on Physical Activity Among People With Arthritis.Musculoskeletal care · 2026Article
- Physical Function and Pain as Predictors of Movement Behaviors in Adults With Arthritis.American journal of health promotion : AJHP · 2026Article
- The Association Between Patient Characteristics and Pain, Physical Function, and Quality of Life Among Patients with Hip Osteoarthritis: Explorative Study with Data from a Randomized Controlled Trial.International journal of sports physical therapy · 2026Article
- Psychiatric, Cardiovascular and Skeletal Risks of Codeine versus Oxycodone in Hip Osteoarthritis: A Population-Based Cohort Study.Drug design, development and therapy · 2026Article
- Are physical activity, sleep, and joint pain associated with physical function and quality of life in individuals with multimorbidity? A cross-sectional analysis of the MOBILIZE trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Chronic disease clusters and health-related quality of life among individuals with musculoskeletal pain: a Northern Finland Birth Cohort 1966 study.Family practice · 2025Article
- Trajectories of physical, mental health and health satisfaction before and after arthritis diagnosis: a UK population-based study.BMC musculoskeletal disorders · 2025Article
- Mental health and health-related quality of life among adults with osteoarthritis: A national population-based study.PloS one · 2025Article
- Mapping the Knowledge Landscape of and Emerging Future Trends in Stem Cell Therapy for Osteoarthritis: A Bibliometric Analysis of the Literature From 1998 to 2024.Journal of multidisciplinary healthcare · 2025Review
- Article
- Dyslipidemia induced inflammation mediated the association between obesity and Osteoarthritis: a population-based study.BMC public health · 2024Article
- A Longitudinal Decline in Walking Speed Is Linked with Coexisting Hypertension and Arthritis in Community-Dwelling Older Adults.Journal of clinical medicine · 2024Article
- Mid-Term Clinical and Radiological Changes in the Ankle Joint in Varus Knee Osteoarthritis Following Total Knee Arthroplasty.Journal of clinical medicine · 2024Article
- Observational
- Personalized Physical Activity Programs for the Management of Knee Osteoarthritis in Individuals with Obesity: A Patient-Centered Approach.Diseases (Basel, Switzerland) · 2023Review
- Therapeutic exercise interventions in rat models of arthritis.Neurobiology of pain (Cambridge, Mass.)Review
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hip and knee osteoarthritis (HKOA) is a chronic disease characterized by joint pain that leads to reduced physical function and health-related quality of life (HRQoL). At present, no cure is available. Clinical trials indicate that people with HKOA benefit from physical activity in several health-related outcomes. However, few studies have evaluated the long-term positive effect of regular physical activity. This study analyzed participants with HKOA from a nationwide population-based cohort (EpiDoC Cohort) to assess the impact of physical activity on patients' physical function and HRQoL over a long-term follow-up. The regular weekly frequency of intentional physical activity was self-reported as non-frequent (0 times/week), frequent (1-2 times/week), or very frequent (≥ 3 times/week). This study followed 1086 participants over a mean period of 4.7 ± 3.4 years, during which 6.3% and 14.9% of participants reported frequent and very frequent physical activity, respectively. Using linear mixed models, we found that frequent (β = - 0.101 [- 0.187, - 0.016]; β = 0.039 [- 0.002, 0.080]) and very frequent physical activity (β = - 0.061 [- 0.118, - 0.004]; β = 0.057 [0.029, 0.084]) were associated with improved physical function and HRQoL over time, respectively, when compared with non-frequent exercise, adjusting for years to baseline, sex, age, years of education, body mass index, multimorbidity, hospitalizations, clinical severity, and unmanageable pain levels. These findings raise awareness of the importance of maintaining exercise/physical activity long term to optimize HRQoL and physical function. Further studies must address barriers and facilitators to improve the adoption of regular physical activity among citizens with HKOA.
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