Evidence map›Paper›PMID 36702951›Full record

ArticleBioprocess and biosystems engineering2023

Increased levels of nerve growth factor accompany oxidative load in recurrent pregnancy loss. Machine learning applied to FT-Raman spectra study.

Joanna Depciuch, Paweł Jakubczyk, Wiesław Paja, Krzysztof Pancerz, Agnieszka Wosiak, Pınar Yalçın Bahat, Ömer Faruk Toto, Huri Bulut, Zozan Guleken

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Article in Bioprocess and biosystems engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 2 countries.

Joanna Depciuch *Institute of Nuclear Physics Polish Academy of Science, 31-342, Krakow, Poland.ORCID http://orcid.org/0000-0003-0168-1701
Paweł JakubczykInstitute of Physics, University of Rzeszow, Rzeszow, Poland.
Wiesław PajaInstitute of Computer Science, University of Rzeszow, Rzeszow, Poland.
Krzysztof PancerzInstitute of Philosophy, John Paul II Catholic University of Lublin, Lublin, Poland.
Agnieszka WosiakInstitute of Information Technology, Lodz University of Technology, Lodz, Poland.
Pınar Yalçın BahatDepartment of Obstetrics and Gynecology, Health Science University Istanbul Kanuni Sultan Suleyman Research Medical Center, Istanbul, Turkey.
Ömer Faruk TotoDepartment of Obstetrics and Gynecology, Health Science University Istanbul Kanuni Sultan Suleyman Research Medical Center, Istanbul, Turkey.
Huri BulutFaculty of Medicine Department of Biochemistry, İstinye University, Istanbul, Turkey.
Zozan Guleken *Faculty of Medicine Department of Physiology, Uskudar University, Istanbul, Turkey. zozanguleken@gmail.com.ORCID http://orcid.org/0000-0002-4136-4447
Sağlık Bilimleri Üniversitesi · TRInstitute of Computer Science · PLInstitute of Nuclear Physics, Polish Academy of Sciences · PLInstitute of Physics · PLIstinye University · TRJohn Paul II Catholic University of Lublin · PLLodz University of Technology · PLÜsküdar University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presented article is focused on developing and validating an efficient, credible, minimally invasive technique based on spectral signatures of blood serum samples in patients with diagnosed recurrent pregnancy loss (RPL) versus healthy individuals who were followed at the Gynecology department. A total of 120 participants, RPL disease (n = 60) and healthy individuals (n = 60), participated in the study. First, we investigated the effect of circulating nerve growth factor (NGF) in RPL and healthy groups. To show NGF's effect, we measured the level of oxidative loads such as Total Antioxidant Level (TAS), Total Oxidant Level (TOS), and Oxidative Stress Index (OSI) with Beckman Coulter AU system and biochemical assays. We find a correlation between oxidative load and NGF level. Oxidative load mainly causes structural changes in the blood. Therefore, we obtained Raman measurements of the participant's serum. Then we selected two Raman regions, 800 and 1800 cm

Indexed as

Abortion, HabitualNerve Growth FactorAntioxidantsFemaleHumansOxidantsOxidative StressPregnancyAntioxidantsNerve Growth FactorOxidantsMachine learningNerve growth factorOxidative Stress IndexRaman spectroscopyRecurrent pregnancy loss

Identifiers

PMID36702951
OpenAlexW4318071667

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.