ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2023
The Longitudinal Association Between Frailty, Cognition, and Quality of Life in Older Europeans.
Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- A systematic review of quality of life (QoL) studies using the CASP scale in older adults.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Pooled it
- Effects of exergaming with a resistance component versus traditional resistance training on sarcopenia in pre-frail and frail nursing home residents: a pilot randomized controlled trial.European geriatric medicine · 2026Trial
- Estimated Cardiorespiratory Fitness and Risk of Incident Frailty in Middle-Aged and Older Adults: A Cross-National Longitudinal Cohort Study.Healthcare (Basel, Switzerland) · 2026Article
- Association between frailty and cognitive function: a pooled analysis of three ageing cohorts.Translational psychiatry · 2025Article
- The mediating role of sarcopenia in the link between loneliness and frailty among nursing home residents: a cross-sectional study.BMC geriatrics · 2025Article
- Association between frailty and quality of life, and the moderating effect of mobile, broadcast and digital media in sub-Saharan Africa: evidence from Kenya.BMC geriatrics · 2025Article
- The association between frailty status and cognitive function in patients with cardiovascular diseases: a nationwide cohort study.Scientific reports · 2025Article
- The relationship between frailty syndrome and quality of life in patients with hypertension: a multidimensional analysis.BMC geriatrics · 2025Article
- Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).Frontiers in aging neuroscience · 2025Article
- Sequential multiple mediating effect of loneliness and family health on physical frailty and willingness to age at home in older adults: a national survey in China.BMC geriatrics · 2024Article
- Frailty Predicting Health-Related Quality of Life Trajectories in Individuals with Sarcopenia in Liver Cirrhosis: Finding from BCAAS Study.Journal of clinical medicine · 2023Article
- Subjective Well-Being and Related Factors among Independent, Healthy, Community-Dwelling Older Adults in Japan.Healthcare (Basel, Switzerland) · 2023Article
- Quality of life and associated factors in institutionalized older adults: implications for gerontological nursing. Analytical study.Revista CuidarteArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
objectivesEvidence on the association between frailty and quality of life (QoL) is mostly limited to cross-sectional studies. Thus, the temporal order and potential mechanisms of this association are largely unknown. Our study examines both the directionality of this association and the role of cognition in this association in longitudinal data.
methodsCross-lagged panel models were employed to examine the temporal relationship between frailty and QoL, as well as cognition's role among 19,649 older adults in Europe. Frailty, QoL, and cognition were assessed using the health deficit index, CASP-12, and 3 standard cognitive tests, respectively.
resultsWe observed a bidirectional association between frailty and QoL and their dynamics. High initial levels of frailty predicted poorer QoL later and vice versa (β = -0.151 and -0.052, p < .001). The early change in frailty predicted the late change in QoL, and vice versa (β = -0.093 and -0.061, p < .001). Frailty or its early change drives this interrelationship. Cognition at Wave 5 partially mediated frailty's effect at Wave 4 on QoL at Wave 6 (indirect effect: β = -0.005, 95% confidence interval = -0.006, -0.004). DISCUSSION: Our findings supported that early prevention of frailty and its risk factors may have more influential protective effects on later physical and mental health, as well as the need for ongoing screening for mental health in aging population. Also, the maintenance of good cognitive performance may help interrupt this possible vicious cycle linking frailty and QoL decline.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.