Evidence map›Paper›PMID 36702730›Full record

ReviewSeminars in nuclear medicine2023

New Approaches for Imaging Bacteria.

Sanjay K Jain

Abstract readReview
In one paragraph

Review in Seminars in nuclear medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Development of NovelACS pharmacology & translational science · 2025
    Article
  2. Synthesis and preclinical evaluation of novelEuropean journal of nuclear medicine and molecular imaging · 2024
    Article
  3. Review
  4. Radiosynthesis and Bioevaluation ofInternational journal of molecular sciences · 2024
    Article
  5. First-in-human infection imaging withFrontiers in nuclear medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Sanjay K JainCenter for Infection and Inflammation Imaging Research, Johns Hopkins University School of Medicine, Baltimore, MD; Center for Tuberculosis Research, Johns Hopkins University School of Medicine, Baltimore, MD; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address: sjain5@jhmi.edu.

Funding

Preclinical modeling to study Tuberculous MeningitisR01AI145435 · NIAID · JOHNS HOPKINS UNIVERSITY · PI JAIN, SANJAY · 2020 to 2024
$4.0M
Measuring Intralesional Drug Exposures in Cavitary TB using Noninvasive In Vivo PET ImagingR01AI153349 · NIAID · JOHNS HOPKINS UNIVERSITY · PI JAIN, SANJAY · 2020 to 2024
$3.8M
Development of 11C-PABA as a bacteria-specific imaging agent for spinal infectionsR01EB025985 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JAIN, SANJAY, WILSON, DAVID M · 2018 to 2021
$2.7M
Molecular Imaging for Pulmonary Infections and InflammationR01HL131829 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI JAIN, SANJAY · 2016 to 2018
$2.2M
NHLBI NIH HHS R01 HL131829NIAID NIH HHS R01 AI145435NIAID NIH HHS R01 AI153349NIBIB NIH HHS R01 EB025985
6 · The paper itself

Abstract

Bacterial infections are a major threat to human health. Rapid and accurate diagnosis of bacterial infections is essential for early interventions and rational use of antibiotic treatments. However, antibiotics are often initiated empirically while diagnostic tests are being performed. Moreover, traditional diagnostic tools, namely microscopy, microbiology and molecular techniques, are dependent upon sampling suspected sites of infection, and then performing tests. This approach is often invasive, labor intensive, time consuming, and subject to the uncertainties of incorrect sampling and contamination. There are currently no imaging approaches for the specific detection of bacterial infections. Therefore, there is a need for new noninvasive approaches to detect, localize and monitor bacterial infections with high sensitivity and specificity.

Indexed as

BacteriaBacterial InfectionsAnti-Bacterial AgentsDiagnostic ImagingHumansAnti-Bacterial Agents

Identifiers

PMID36702730
PMCPMC9992343

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.