ArticleAge and ageing2023
Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed.
Article in Age and ageing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03984396 (Optimal Medication Management in Alzheimer's Disease and Dementia), which is not on this map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Optimal Medication Management in Alzheimer's Disease and Dementia
Who cites it
5 citing papers in PubMed.
- Feasibility and Acceptability of Engaging Care Partners of Persons Living With Dementia With Electronic Outreach for Deprescribing.The Gerontologist · 2025Article
- Article
- Co-Designing a Consult Patient Decision Aid for Continuation Versus Deprescribing Cholinesterase Inhibitors in People Living with Dementia.Drugs & aging · 2024Article
- Influence of chronic medical conditions on older patients' willingness to deprescribe medications: a cross-sectional study.BMC geriatrics · 2024Article
- Medication misuse and overuse in community-dwelling persons with dementia.Journal of the American Geriatrics Society · 2023Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
backgroundpeople living with cognitive impairment commonly take multiple medications including potentially inappropriate medications (PIMs), which puts them at risk of medication related harms.
aimsto explore willingness to have a medication deprescribed of older people living with cognitive impairment (dementia or mild cognitive impairment) and multiple chronic conditions and assess the relationship between willingness, patient characteristics and belief about medications.
methodscross-sectional study using results from the revised Patients' Attitudes Towards Deprescribing questionnaire (rPATDcog) collected as baseline data in the OPTIMIZE study, a pragmatic, cluster-randomised trial educating patients and clinicians about deprescribing. Eligible participants were 65+, diagnosed with dementia or mild cognitive impairment, and prescribed at least five-long-term medications.
resultsthe questionnaire was mailed to 1,409 intervention patients and 553 (39%) were returned and included in analysis. Participants had a mean age of 80.1 (SD 7.4) and 52.4% were female. About 78.5% (431/549) of participants said that they would be willing to have one of their medications stopped if their doctor said it was possible. Willingness to deprescribe was negatively associated with getting stressed when changes are made and with previously having a bad experience with stopping a medication (P < 0.001 for both).
conclusionmost older people living with cognitive impairment are willing to deprescribe. Addressing previous bad experiences with stopping a medication and stress when changes are made to medications may be key points to discuss during deprescribing conversations.
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