Evidence map›Paper›PMID 36702472›Full record

ArticleJournal of the National Cancer Institute2023

COVID-19 severity by vaccination status in the NCI COVID-19 and Cancer Patients Study (NCCAPS).

Ana F Best, Melissa Bowman, Jessica Li, Grace E Mishkin, Andrea Denicoff, Marwa Shekfeh, Larry Rubinstein, Jeremy L Warner, Brian Rini, Larissa A Korde

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Journal of the National Cancer Institute, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Guideline
  2. Vaccines for preventing infections in adults with solid tumours.The Cochrane database of systematic reviews · 2025
    Pooled it
  3. Vaccination of Adults With Cancer: ASCO Guideline.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Guideline
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ana F BestBiometric Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, MD, USA.
Melissa BowmanEmmes Corporation, Rockville, MD, USA.
Jessica LiBiometric Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, MD, USA.
Grace E MishkinClinical Investigations Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, MD, USA.
Andrea DenicoffClinical Investigations Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, MD, USA.
Marwa ShekfehBiometric Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, MD, USA.
Larry RubinsteinBiometric Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, MD, USA.
Jeremy L WarnerVanderbilt Ingram Cancer Center, Nashville, TN, USA.
Brian RiniVanderbilt Ingram Cancer Center, Nashville, TN, USA.
Larissa A KordeClinical Investigations Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, MD, USA.ORCID 0000-0001-9393-7019
National Cancer Institute · USVanderbilt University · USEmmes (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the association of SARS CoV-2 vaccination with COVID-19 severity in a longitudinal study of adult cancer patients with COVID-19. A total of 1610 patients who were within 14 days of an initial positive SARS CoV-2 test and had received recent anticancer treatment or had a history of stem cell transplant or CAR-T cell therapy were enrolled between May 21, 2020, and February 1, 2022. Patients were considered fully vaccinated if they were 2 weeks past their second dose of mRNA vaccine (BNT162b2 or mRNA-1273) or a single dose of adenovirus vector vaccine (Ad26.COV2.S) at the time of positive SARS CoV-2 test. We defined severe COVID-19 disease as hospitalization for COVID-19 or death within 30 days. Vaccinated patients were significantly less likely to develop severe disease compared with those who were unvaccinated (odds ratio = 0.44, 95% confidence interval = 0.28 to 0.72, P < .001). These results support COVID-19 vaccination among cancer patients receiving active immunosuppressive treatment.

Indexed as

COVID-19NeoplasmsAd26COVS1AdultBNT162 VaccineCOVID-19 VaccinesHumansLongitudinal StudiesSARS-CoV-2VaccinationAd26COVS1BNT162 VaccineCOVID-19 Vaccines

Identifiers

PMID36702472
PMCPMC10165483
OpenAlexW4318263144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.