Evidence map›Paper›PMID 36702062›Full record

Trial reportComprehensive psychiatry2023

Views about neuromodulation interventions for depression by stakeholder group, treatment modality, and depression severity.

L Y Cabrera, E D Achtyes, R Bluhm, A M McCright

Abstract readRandomized Controlled TrialVideo-Audio Media
In one paragraph

Trial report in Comprehensive psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Four dimensions of individualization in brain stimulation for psychiatric disorders: context, target, dose, and timing.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

L Y CabreraPennsylvania State University, University Park, PA 18602, USA. Electronic address: lcabrera@psu.edu.
E D AchtyesMichigan State University, Grand Rapids, MI 49503, USA. Electronic address: EricAchtyes@cherryhealth.com.
R BluhmMichigan State University, 368 Farm Lane, East Lansing, MI 48824, USA. Electronic address: rbluhm@msu.edu.
A M McCrightMichigan State University, 509 East Circle Drive, Room 317, East Lansing, MI 48824, USA. Electronic address: mccright@msu.edu.

Funding

Is the Treatment Perceived to be Worse than the Disease?: Ethical Concerns and Attitudes towards Psychiatric Electroceutical InterventionsRF1MH117802 · NIMH · PENNSYLVANIA STATE UNIVERSITY, THE · PI CABRERA TRUJILLO, LAURA YENISA · 2018 to 2018
$1.3M
NIMH NIH HHS RF1 MH117802
6 · The paper itself

Abstract

backgroundThe past few decades have seen the emergence both of new neuromodulation treatment protocols and novel applications of standard neuromodulation interventions in psychiatry. Yet little is known about different stakeholders' views about these interventions.

methodsWe administered an online survey with an embedded video vignette experiment to four national samples: the general public (N = 1022), caregivers for people with depression (N = 1026), patients living with depression (N = 1050), and board-certified psychiatrists (N = 505). We randomly assigned subjects to one of eight conditions in our full factorial design: four neuromodulation interventions [electroconvulsive therapy, repetitive transcranial magnetic stimulation, deep brain stimulation, or adaptive brain implants] by two depression severity levels [moderate or severe]. In this paper we present results from ANOVA and linear regression models explaining how views about these four neuromodulation interventions-as measured in five attitudinal scales (general affect, perceived influence on self, perceived benefit, perceived risk, and perceived invasiveness)-vary by (1) intervention, (2) depression severity, and/or (3) stakeholder group.

resultsOur results provide evidence that psychiatrists views differ significantly in important ways from other stakeholder groups. Type of intervention also shaped participants' attitudes, including perceptions of invasiveness, effectiveness, and safety.

conclusionsGiven the differing affective valence among stakeholders and the differences found by modality and stakeholder groups across the different scales, future targeted educational initiatives could be developed to help address key misunderstandings and misinformed perceptions.

Indexed as

DepressionElectroconvulsive TherapyBrainHumansSurveys and QuestionnairesTranscranial Magnetic StimulationAttitudesDepressionElectroceuticalsNeuroethicsNeuromodulationNeurostimulationStakeholders

Identifiers

PMID36702062
PMCPMC9993717

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.