Evidence map›Paper›PMID 36701676›Full record

Trial reportAmerican journal of respiratory and critical care medicine2023

Allergen Immunotherapy Enhances Airway Epithelial Antiviral Immunity in Patients with Allergic Asthma (VITAL Study): A Double-Blind Randomized Controlled Trial.

Christian Woehlk, Sangeetha Ramu, Asger Sverrild, Juan José Nieto-Fontarigo, Sara Vázquez-Mera, Samuel Cerps, Alexis Pulga, Louise Munkholm Andreasson, Lise Lotte Eriksen, Nanna Dyhre-Petersen and 5 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
14.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 58 citations in OpenAlex.

  1. Recent advances in allergen immunotherapy.Chinese medical journal · 2026
    Review
  2. Review
  3. Review
  4. The rhinovirus puzzle: Linking virus and host factors to childhood asthma.The Journal of allergy and clinical immunology · 2026
    Review
  5. Asthma endotypes and theratypes.Chinese medical journal pulmonary and critical care medicine · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Type 2 immunity in allergic diseases.Cellular & molecular immunology · 2025
    Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Observational
  20. The epithelial era of asthma research: knowledge gaps and future direction for patient care.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 4 countries.

Christian WoehlkRespiratory Research Unit, Department of Respiratory and Infectious Medicine, Bispebjerg Hospital, Copenhagen, Denmark.ORCID 0000-0003-4605-1308
Sangeetha RamuUnit of Respiratory Immunopharmacology, Department of Experimental Medical Science, Lund University, Lund, Sweden.ORCID 0000-0002-1086-027X
Asger SverrildRespiratory Research Unit, Department of Respiratory and Infectious Medicine, Bispebjerg Hospital, Copenhagen, Denmark.ORCID 0000-0003-0625-6405
Juan José Nieto-FontarigoUnit of Respiratory Immunopharmacology, Department of Experimental Medical Science, Lund University, Lund, Sweden.ORCID 0000-0002-4647-1508
Sara Vázquez-MeraDepartment of Biochemistry and Molecular Biology, University of Santiago de Compostela, Santiago de Compostela, Spain; and.
Samuel CerpsUnit of Respiratory Immunopharmacology, Department of Experimental Medical Science, Lund University, Lund, Sweden.
Alexis PulgaRespiratory Research Unit, Department of Respiratory and Infectious Medicine, Bispebjerg Hospital, Copenhagen, Denmark.
Louise Munkholm AndreassonRespiratory Research Unit, Department of Respiratory and Infectious Medicine, Bispebjerg Hospital, Copenhagen, Denmark.
Lise Lotte EriksenRespiratory Research Unit, Department of Respiratory and Infectious Medicine, Bispebjerg Hospital, Copenhagen, Denmark.ORCID 0000-0003-3974-2573
Nanna Dyhre-PetersenRespiratory Research Unit, Department of Respiratory and Infectious Medicine, Bispebjerg Hospital, Copenhagen, Denmark.
Mandy MenzelRespiratory Research Unit, Department of Respiratory and Infectious Medicine, Bispebjerg Hospital, Copenhagen, Denmark.ORCID 0000-0003-1286-2022
Ditte K KleinRespiratory Research Unit, Department of Respiratory and Infectious Medicine, Bispebjerg Hospital, Copenhagen, Denmark.ORCID 0000-0003-1068-6723
Susanne HansenRespiratory Research Unit, Department of Respiratory and Infectious Medicine, Bispebjerg Hospital, Copenhagen, Denmark.ORCID 0000-0002-9550-6703
Lena UllerUnit of Respiratory Immunopharmacology, Department of Experimental Medical Science, Lund University, Lund, Sweden.ORCID 0000-0003-1842-148X
Celeste PorsbjergRespiratory Research Unit, Department of Respiratory and Infectious Medicine, Bispebjerg Hospital, Copenhagen, Denmark.ORCID 0000-0003-4825-9436
Bispebjerg Hospital · DKLund University · SEUniversidade de Santiago de Compostela · ESUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsthmaRhinitis, AllergicAdultAllergensAnimalsAntigens, DermatophagoidesAntiviral AgentsDesensitization, ImmunologicHumansPoly CPyroglyphidaeTreatment OutcomeTumor Necrosis Factor-alphaAllergensAntigens, DermatophagoidesAntiviral AgentsPoly CTumor Necrosis Factor-alphaairway resistanceallergen immunotherapyallergic asthmaantiviral immunitybronchial epithelium

Identifiers

PMID36701676
PMCPMC10161758
OpenAlexW4318161849

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.