Evidence map›Paper›PMID 36701255›Full record

ArticleMMWR. Morbidity and mortality weekly report2023

Scale-Up of HIV Antiretroviral Therapy and Estimation of Averted Infections and HIV-Related Deaths - Uganda, 2004-2022.

Emilio Dirlikov, Joseph Kamoga, Stella Alamo Talisuna, Jennifer Namusobya, Daniel E Kasozi, Juliet Akao, Estella Birabwa, Jennifer A Ward, Bill Elur, Ray W Shiraishi and 11 more

Open access · diamondAbstract read
In one paragraph

Article in MMWR. Morbidity and mortality weekly report, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Emilio Dirlikov
Joseph Kamoga
Stella Alamo Talisuna
Jennifer Namusobya
Daniel E Kasozi
Juliet Akao
Estella Birabwa
Jennifer A Ward
Bill Elur
Ray W Shiraishi
Carl Corcoran
Vamsi Vasireddy
Richard Nelson
Lisa J Nelson
Mary Borgman
Eleanor Namusoke Magongo
Linda Nabitaka Kisaakye
Cordelia Katureebe
Wilford Kirungi
Joshua Musinguzi
PEPFAR Uganda

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

On January 28, 2003, the U.S. President's Emergency Plan for AIDS Relief (PEPFAR), the largest commitment by any nation to address a single disease in history, was announced.* In April 2004, the first person in the world to receive PEPFAR-supported antiretroviral therapy (ART) was a man aged 34 years in Uganda. Effective ART reduces morbidity and mortality among persons with HIV infection (1) and prevents both mother-to-child transmission (MTCT) (2) and sexual transmission once viral load is suppressed to undetectable levels (<200 viral copies/mL) (3). By September 2022, more than 1.3 million persons with HIV infection in Uganda were receiving PEPFAR-supported ART, an increase of approximately 5,000% from September 2004. As indicators of the ART program's effectiveness, a proxy MTCT rate decreased 77%, from 6.4% in 2010 to 1.5% in 2022, and the viral load suppression rate (<1,000 viral copies/mL) increased 3%, from 91% in 2016 to 94% in September 2022. During 2004-2022, ART scale-up helped avert nearly 500,000 HIV infections, including more than 230,000 infections among HIV-exposed infants, and approximately 600,000 HIV-related deaths. Going forward, efforts will focus on identifying all persons with HIV infection and rapidly linking them to effective ART. PEPFAR remains committed to continued strong partnership with the Government of Uganda, civil society, and other development partners toward sustainable solutions aligned with the Joint United Nations Programme on HIV/AIDS (UNAIDS) fast-track strategy to ending the global AIDS epidemic by 2030

Indexed as

Acquired Immunodeficiency SyndromeHIV InfectionsAnti-Retroviral AgentsFemaleHumansInfantInfectious Disease Transmission, VerticalInternational CooperationMaleUgandaAnti-Retroviral Agents

Identifiers

PMID36701255
PMCPMC9925129
OpenAlexW4318165884

What OpenQuestion holds

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LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.