Evidence map›Paper›PMID 36701048›Full record

ArticleVirus genes2023

Characterization and genome analysis of a novel phage Kayfunavirus TM1.

Kaiou Han, Xinyu Mao, Hui Liu, Yuxing Wu, Yizhou Tan, Ziyong Li, Runwen Ma, Yinan Li, Lei Li, Leping Wang and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Virus genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Isolation and characterization of a novel phage targeting Klebsiella pneumoniae K2 capsular type.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Genome sequencing of3 Biotech · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Kaiou HanCollege of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Xinyu MaoCollege of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Hui LiuCollege of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Yuxing WuCollege of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Yizhou TanCollege of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Ziyong LiCollege of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Runwen MaCollege of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Yinan LiCollege of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Lei LiCollege of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Leping WangCollege of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Yan ShiCollege of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Yajie CaoCollege of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Hao PengGuangxi Veterinary Research Institute, Nanning, 530004, Guangxi, China.
Xun LiCollege of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China.
Xiaoye WangCollege of Animal Science and Technology, Guangxi University, Nanning, 530004, Guangxi, People's Republic of China. xywang@gxu.edu.cn.
Guangxi University · CNGuangxi Veterinary Research Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Escherichia coli is a common conditional pathogen, for which antibiotic therapy is considered an effective treatment. The imprudent use of antibiotics has led to the increase of multiple-antibiotic-resistant E. coli species. With the incidence of antibiotic resistance reaching a crisis point, it is imperative to find alternative treatments for multidrug-resistant infections. Using phage for pathogen control is a promising treatment option to combat bacterial resistance. In this study, a novel virulent Podoviridae phage Kayfunavirus TM1 infecting Escherichia coli was isolated from pig farm sewage in Guangxi, China. The one-step growth curve with the optimal multiplicity of infection of 0.01 revealed a latent period of 10 min and a burst size of 50 plaque-forming units per cell. The stability test reveals that it is stable from 4 to 60 °C and pH from 3 to 11. The double-stranded DNA genome of phage Kayfunavirus TM1 is composed of 39,948 base pairs with a GC content of 50.03%.

Indexed as

BacteriophagesAnimalsAnti-Bacterial AgentsChinaDNA, ViralEscherichia coliGenome, ViralSwineAnti-Bacterial AgentsDNA, ViralBacteriophagePhage characterizationTM1Whole-genomic analysis

Identifiers

PMID36701048
OpenAlexW4318067237

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.