ArticleJournal of virology2023
Virology under the Microscope-a Call for Rational Discourse.
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Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13citing papers in PubMed
–field-weighted citation impact
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Public trust in science has declined since COVID - virologists need to unite around safety standards.Nature · 2025Article
- Principal Investigator Responsibility for Flagging Research with Dual-Use or Pandemic Risk.Applied biosafety : journal of the American Biological Safety Association · 2025Article
- Virologist Opinions: An Important Component for the Governance of the Convergence of Artificial Intelligence and Dual-Use Research of Concern.Applied biosafety : journal of the American Biological Safety Association · 2025Article
- Future pandemics and the urge to 'do something'.Journal of medical ethics · 2025Article
- The Application of DNA Viruses to Biotechnology.Viruses · 2025Review
- Development of learning objectives to support undergraduate virology curriculum guidelines.Journal of microbiology & biology education · 2024Article
- Dual-use research and research using enhanced pathogens in high-income countries: whose business?mSphere · 2024Article
- SARS-CoV-2 resistance to monoclonal antibodies and small-molecule drugs.Cell chemical biology · 2024Review
- Virology-the path forward.Journal of virology · 2024Article
- Article
- Article
- Statement in Support of: "Virology under the Microscope-a Call for Rational Discourse".mSphere · 2023Article
- Statement in Support of: "Virology under the Microscope-a Call for Rational Discourse".Journal of virology · 2023Article
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Authors and funding
156 authors.
Felicia GoodrumDepartment of Immunobiology, BIO5 Institute, University of Arizona, Tucson, Arizona, USA.ORCID 0000-0002-6646-7290
Anice C LowenDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0002-9829-112X
Seema LakdawalaDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0002-7679-2150
James AlwineDepartment of Immunobiology, BIO5 Institute, University of Arizona, Tucson, Arizona, USA.
Arturo CasadevallDepartment of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0002-9402-9167
Michael J ImperialeDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.
Walter AtwoodBrown University, Providence, Rhode Island, USA.ORCID 0000-0002-3763-9073
Daphne AvgoustiFred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Joel BainesCornell University, Ithaca, New York, USA.ORCID 0000-0002-6397-2830
Bruce BanfieldQueen's University, Kingston, Ontario, Canada.ORCID 0000-0002-5989-6695
Lawrence BanksInternational Centre for Genetic Engineering and Biotechnology, Trieste, Italy.
Sumita Bhaduri-McIntoshUniversity of Florida, Gainesville, Florida, USA.ORCID 0000-0003-2946-9497
Deepta BhattacharyaUniversity of Arizona, Tucson, Arizona, USA.
Daniel Blanco-MeloFred Hutchinson Cancer Research Center, Seattle, Washington, USA.
David BloomUniversity of Florida, Gainesville, Florida, USA.ORCID 0000-0001-5935-8494
Adrianus BoonUniversity of Illinois at Urbana-Champaign, Urbana, Illinois, USA.ORCID 0000-0002-4700-8224
Steeve BoulantUniversity of Florida, Gainesville, Florida, USA.ORCID 0000-0001-8614-4993
Curtis BrandtUniversity of Wisconsin-Madison, Madison, Wisconsin, USA.
Andrew BroadbentUniversity of Maryland, College Park, Maryland, USA.ORCID 0000-0002-4716-1835
Christopher BrookeUniversity of Illinois at Urbana-Champaign, Urbana, Illinois, USA.ORCID 0000-0002-6815-1193
Craig CameronUniversity of North Carolina, Chapel Hill, North Carolina, USA.
Samuel CamposUniversity of Arizona, Tucson, Arizona, USA.ORCID 0000-0003-1540-9821
Patrizia CaposioOregon Health and Science University, Beaverton, Oregon, USA.ORCID 0000-0001-7579-849X
Gary ChanSUNY Upstate Medical University, Syracuse, New York, USA.ORCID 0000-0001-8209-9777
Anna CliffeUniversity of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0003-1136-5171
John CoffinTufts University, Boston, Massachusetts, USA.
Kathleen CollinsUniversity of Michigan, Ann Arbor, Michigan, USA.
Blossom DamaniaUniversity of North Carolina, Chapel Hill, North Carolina, USA.ORCID 0000-0002-9205-1774
Matthew DaughertyUniversity of California, San Diego, La Jolla, California, USA.
Kari DebbinkJohns Hopkins University, Baltimore, Maryland, USA.
James DeCaprioHarvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-0896-167X
Terence DermodyUniversity of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-1853-8741
Jimmy DikeakosWestern University, London, Ontario, Canada.ORCID 0000-0001-8141-5395
Daniel DiMaioYale University, New Haven, Connecticut, USA.ORCID 0000-0002-2060-5977
Rhoel DinglasanUniversity of Florida, Gainesville, Florida, USA.
W Paul DuprexUniversity of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-1716-6376
Rebecca DutchUniversity of Kentucky, Lexington, Kentucky, USA.ORCID 0000-0002-5220-8247
Nels EldeUniversity of Utah, Salt Lake City, Utah, USA.
Michael EmermanFred Hutchinson Cancer Research Center, Seattle, Washington, USA.ORCID 0000-0002-4181-6335
Lynn EnquistPrinceton University, Princeton, New Jersey, USA.ORCID 0000-0001-9968-8586
Bentley FaneUniversity of Arizona, Tucson, Arizona, USA.ORCID 0000-0002-3984-1726
Ana Fernandez-SesmaIcahn School of Medicine at Mount Sinai, New York, New York, USA.
Michelle FlennikenMontana State University, Bozeman, Montana, USA.
Lori FrappierUniversity of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-0110-5472
Matthew FriemanUniversity of Maryland, College Park, Maryland, USA.ORCID 0000-0003-0107-0775
Klaus FruehOregon Health and Science University, Beaverton, Oregon, USA.
Michaela GackFlorida Research and Innovation Center, Port Saint Lucie, Florida, USA.ORCID 0000-0002-2163-2598
Marta GagliaUniversity of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-1791-0663
Tom GallagherLoyola University, Maywood, Illinois, USA.ORCID 0000-0002-8601-5961
Denise GallowayFred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Adolfo García-SastreIcahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0002-6551-1827
Adam GeballeFred Hutchinson Cancer Research Center, Seattle, Washington, USA.ORCID 0000-0002-9279-6653
Britt GlaunsingerUniversity of California, Berkeley, Berkeley, California, USA.ORCID 0000-0003-0479-9377
Stephen GoffColumbia University, New York, New York, USA.ORCID 0000-0002-9679-0582
Alexander GreningerUniversity of Washington, Seattle, Washington, USA.ORCID 0000-0002-7443-0527
Meaghan HancockOregon Health and Science University, Beaverton, Oregon, USA.ORCID 0000-0003-2945-0147
Eva HarrisUniversity of California, Berkeley, Berkeley, California, USA.ORCID 0000-0002-7238-4037
Nicholas HeatonDuke University, Durham, North Carolina, USA.ORCID 0000-0002-5307-3428
Mark HeiseUniversity of North Carolina, Chapel Hill, North Carolina, USA.ORCID 0000-0001-5829-8477
Ekaterina HeldweinTufts University, Boston, Massachusetts, USA.ORCID 0000-0003-3113-6958
Brenda HogueArizona State University, Tempe, Arizona, USA.
Stacy HornerDuke University, Durham, North Carolina, USA.ORCID 0000-0002-9351-7409
Edward HutchinsonMRC-University of Glasgow, Glasgow, United Kingdom.
Joseph HyserBaylor University, Houston, Texas, USA.
William JacksonArizona State University, Tempe, Arizona, USA.ORCID 0000-0002-9832-0584
Robert KalejtaDuke University, Durham, North Carolina, USA.ORCID 0000-0002-7116-3355
Jeremy KamilLouisiana State University, Shreveport, Louisiana, USA.ORCID 0000-0001-8422-7656
Stephanie KarstUniversity of Florida, Gainesville, Florida, USA.
Frank KirchhoffUlm University, Ulm, Germany.ORCID 0000-0002-7052-2360
David KnipeHarvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-1554-6236
Timothy KowalikUniversity of Massachusetts, Worcester, Massachusetts, USA.
Michael LagunoffUniversity of Washington, Seattle, Washington, USA.
Laimonis LaiminsNorthwestern University, Chicago, Illinois, USA.ORCID 0000-0002-6314-623X
Ryan LangloisUniversity of Minnesota, Minneapolis, Minnesota, USA.
Adam LauringUniversity of Michigan, Ann Arbor, Michigan, USA.
Benhur LeeIcahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0003-0760-1709
David LeibDartmouth College, Lebanon, New Hampshire, USA.
Shan-Lu LiuThe Ohio State University, Columbus, Ohio, USA.ORCID 0000-0003-1620-3817
Richard LongneckerNorthwestern University, Chicago, Illinois, USA.ORCID 0000-0001-7175-6217
Carolina LopezWashington University, St. Louis, Missouri, USA.ORCID 0000-0002-7669-6572
Micah LuftigDuke University, Durham, North Carolina, USA.ORCID 0000-0002-2964-1907
Jennifer LundFred Hutchinson Cancer Research Center, Seattle, Washington, USA.ORCID 0000-0003-3284-979X
Balaji ManicassamyUniversity of Iowa, Iowa City, Iowa, USA.ORCID 0000-0003-1964-0967
Grant McFaddenArizona State University, Tempe, Arizona, USA.ORCID 0000-0002-2556-3526
Michael McIntoshUniversity of Florida, Gainesville, Florida, USA.
Andrew MehleUniversity of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-6060-4330
W Allen MillerIowa State University, Ames, Iowa, USA.ORCID 0000-0003-0603-2751
Ian MohrNew York University, New York, New York, USA.
Cary MoodyUniversity of North Carolina, Chapel Hill, North Carolina, USA.ORCID 0000-0002-1991-0640
Nathaniel MoormanUniversity of North Carolina, Chapel Hill, North Carolina, USA.
Anne MosconaColumbia University, New York, New York, USA.ORCID 0000-0002-1796-8320
Bryan MounceLoyola University, Maywood, Illinois, USA.ORCID 0000-0003-1710-5362
Joshua MungerUniversity of Rochester, Rochester, New York, USA.ORCID 0000-0001-5379-9440
Karl MüngerTufts University, Boston, Massachusetts, USA.
Eain MurphySUNY Upstate Medical University, Syracuse, New York, USA.ORCID 0000-0003-3449-5024
Mojgan NaghaviNorthwestern University, Chicago, Illinois, USA.
Jay NelsonOregon Health and Science University, Beaverton, Oregon, USA.
Christopher NeufeldtEmory University, Atlanta, Georgia, USA.
Janko NikolichUniversity of Arizona, Tucson, Arizona, USA.
Christine O'ConnorCleveland Clinic, Cleveland, Ohio, USA.ORCID 0000-0003-4943-3774
Akira OnoUniversity of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0001-7841-851X
Walter OrensteinEmory University, Atlanta, Georgia, USA.
David OrnellesWake Forest University, Winston-Salem, North Carolina, USA.
Jing-Hsiung OuUniversity of Southern California, Los Angeles, California, USA.ORCID 0000-0002-8274-5705
John ParkerCornell University, Ithaca, New York, USA.ORCID 0000-0003-4487-4175
Colin ParrishCornell University, Ithaca, New York, USA.ORCID 0000-0002-1836-6655
Andrew PekoszJohns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0003-3248-1761
Philip PellettWayne State University, Detroit, Michigan, USA.ORCID 0000-0002-8536-8343
Julie PfeifferUniversity of Texas, Dallas, Texas, USA.ORCID 0000-0003-2973-4895
Richard PlemperGeorgia State University, Atlanta, Georgia, USA.
Stephen PolyakUniversity of Washington, Seattle, Washington, USA.ORCID 0000-0001-7475-9827
John PurdyUniversity of Arizona, Tucson, Arizona, USA.ORCID 0000-0001-7460-7567
Dohun PyeonMichigan State University, East Lansing, Michigan, USA.ORCID 0000-0003-1970-844X
Miguel Quinones-MateuWestern University, London, Ontario, Canada.
Rolf RenneUniversity of Florida, Gainesville, Florida, USA.ORCID 0000-0001-7391-8806
Charles RiceThe Rockefeller University, New York, New York, USA.
John SchogginsUniversity of Texas, Dallas, Texas, USA.ORCID 0000-0002-7944-6800
Richard RollerUniversity of Iowa, Iowa City, Iowa, USA.ORCID 0000-0001-8340-3224
Charles RussellSt. Jude Children's Research Hospital, Memphis, Tennessee, USA.ORCID 0000-0001-5683-3990
Rozanne Sandri-GoldinUniversity of California, Irvine, Irvine, California, USA.
Martin SappLouisiana State University, Shreveport, Louisiana, USA.ORCID 0000-0003-3916-8890
Luis SchangCornell University, Ithaca, New York, USA.ORCID 0000-0002-5789-8590
Scott SchmidUniversity of Colorado, Boulder, Colorado, USA.
Stacey Schultz-CherrySt. Jude Children's Research Hospital, Memphis, Tennessee, USA.ORCID 0000-0002-2021-727X
Bert SemlerUniversity of California, Irvine, Irvine, California, USA.ORCID 0000-0002-2424-5155
Thomas ShenkPrinceton University, Princeton, New Jersey, USA.
Guido SilvestriUniversity of Kentucky, Lexington, Kentucky, USA.
Viviana SimonIcahn School of Medicine at Mount Sinai, New York, New York, USA.
Gregory SmithNorthwestern University, Chicago, Illinois, USA.ORCID 0000-0001-9644-8472
Jason SmithUniversity of Washington, Seattle, Washington, USA.ORCID 0000-0001-6727-5269
Katherine SpindlerUniversity of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0002-9829-6051
Megan StaniferUniversity of Florida, Gainesville, Florida, USA.
Kanta SubbaraoThe Peter Doherty Institute, Melbourne, Victoria, Australia.ORCID 0000-0003-1713-3056
Wesley SundquistUniversity of Utah, Salt Lake City, Utah, USA.
Mehul SutharEmory University, Atlanta, Georgia, USA.ORCID 0000-0002-2686-8380
Troy SuttonThe Pennsylvania State University, University Park, Pennsylvania, USA.ORCID 0000-0002-7880-4784
Andrew TaiUniversity of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-6877-450X
Vera TarakanovaMedical College of Wisconsin, Milwaukee, Wisconsin, USA.ORCID 0000-0002-9499-088X
Benjamin tenOeverNew York University, New York, New York, USA.ORCID 0000-0003-0324-3078
Scott TibbettsUniversity of Florida, Gainesville, Florida, USA.ORCID 0000-0001-8889-1642
Stephen TompkinsUniversity of Georgia, Athens, Georgia, USA.ORCID 0000-0002-1523-5588
Zsolt TothUniversity of Florida, Gainesville, Florida, USA.ORCID 0000-0001-6628-3945
Koenraad van DoorslaerUniversity of Arizona, Tucson, Arizona, USA.ORCID 0000-0002-2985-0733
Marco VignuzziA*STAR Infectious Diseases Labs, Singapore.
Nicholas WallaceKansas State University, Manhattan, Kansas, USA.ORCID 0000-0002-3971-716X
Derek WalshNorthwestern University, Chicago, Illinois, USA.ORCID 0000-0002-8756-4655
Michael WeekesUniversity of Cambridge, Cambridge, United Kingdom.
Jason WeinbergUniversity of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-4768-4361
Matthew WeitzmanUniversity of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-9713-167X
Sandra WellerUniversity of Connecticut, Farmington, Connecticut, USA.ORCID 0000-0002-4519-6276
Sean WhelanWashington University, St. Louis, Missouri, USA.ORCID 0000-0003-1564-8590
Elizabeth WhiteUniversity of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-7378-7690
Bryan WilliamsMonash University, Clayton, Victoria, Australia.
Christiane WobusUniversity of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0001-5286-0924
Scott WongOregon Health and Science University, Beaverton, Oregon, USA.
Andrew YurochkoLouisiana State University, Shreveport, Louisiana, USA.ORCID 0000-0002-6452-5813
Funding
"Project 3" MHV68 IncRNA/miRNA interaction in latency and lympomagenesisP01CA214091 · NCI · UNIVERSITY OF FLORIDA · PI Scott A. Tibbetts · 2017 to 2026
$15.9MPractices CoreUC7AI180311 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI William Paul Duprex · 2023 to 2026
$13.2MControl of Translation in Herpesvirus Infected Cells - Resubmission - 1R01GM056927 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Ian J Mohr · 1999 to 2026
$7.6MVirus Host Interactions that Regulate Translation in Cells Infected with HSV-1R01AI073898 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MOHR, IAN J · 2008 to 2020
$5.0MPathogen-driven evolution of innate antiviral defense mechanismsR35GM133633 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Matthew Daugherty · 2019 to 2026
$3.3MEPITRANSCRIPTOMIC REGULATION OF CYTOMEGALOVIRUS INFECTIONR01AI152543 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DEPLEDGE, DANIEL PEARCE, MOHR, IAN J · 2020 to 2025
$2.7MNCI NIH HHS P01 CA214091NIAID NIH HHS R01 AI073898NIAID NIH HHS R01 AI152543NIAID NIH HHS UC7 AI180311NIGMS NIH HHS R01 GM056927NIGMS NIH HHS R35 GM133633
Abstract
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease burden with vaccines and antivirals. Despite this long history, the COVID-19 pandemic has brought unprecedented attention to the field of virology. Some of this attention is focused on concern about the safe conduct of research with human pathogens. A small but vocal group of individuals has seized upon these concerns - conflating legitimate questions about safely conducting virus-related research with uncertainties over the origins of SARS-CoV-2. The result has fueled public confusion and, in many instances, ill-informed condemnation of virology. With this article, we seek to promote a return to rational discourse. We explain the use of gain-of-function approaches in science, discuss the possible origins of SARS-CoV-2 and outline current regulatory structures that provide oversight for virological research in the United States. By offering our expertise, we - a broad group of working virologists - seek to aid policy makers in navigating these controversial issues. Balanced, evidence-based discourse is essential to addressing public concern while maintaining and expanding much-needed research in virology.
Indexed as
ResearchVirologyVirus DiseasesCOVID-19HumansInformation DisseminationPandemicsPolicy MakingSARS-CoV-2VirusesbiosafetyCoronavirusCOVID-19DURCGain of functioninfluenzapandemicSARS-CoV-2vaccineszoonosis
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.