Evidence map›Paper›PMID 36700474›Full record

ArticleBioengineered2022

Gypenosides regulate autophagy through Sirt1 pathway and the anti-inflammatory mechanism of mitochondrial autophagy in systemic lupus erythematosus.

Jin-Yong Ke, Zhi-Yong Liu, Yun-Han Wang, Shi-Ming Chen, Jing Lin, Fang Hu, Yu-Fang Wang

RetractedOpen access · goldAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Therapeutic Potential ofNutrients · 2025
    Trial
  2. Review
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jin-Yong KeDepartment of Hematology, Huangshi Central Hospital, Edong Healthcare Group (Affiliated Hospital of Hubei Polytechnic University), Huangshi, Hubei, China.
Zhi-Yong LiuDepartment of Rheumatism Immunity, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Yun-Han WangGuangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Shi-Ming ChenDepartment of Hematology, Huangshi Central Hospital, Edong Healthcare Group (Affiliated Hospital of Hubei Polytechnic University), Huangshi, Hubei, China.
Jing LinDepartment of Hematology, Huangshi Central Hospital, Edong Healthcare Group (Affiliated Hospital of Hubei Polytechnic University), Huangshi, Hubei, China.
Fang HuDepartment of Clinical Laboratory, Huangshi Central Hospital, Edong Healthcare Group (Affiliated Hospital of Hubei Polytechnic University), Huangshi, Hubei, China.
Yu-Fang WangDepartment of Hematology, Huangshi Central Hospital, Edong Healthcare Group (Affiliated Hospital of Hubei Polytechnic University), Huangshi, Hubei, China.
Guangzhou University of Chinese Medicine · CNHubei Polytechnic University · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To study the mechanism of

Indexed as

Lupus Erythematosus, SystemicSirtuin 1AMP-Activated Protein KinasesAnimalsAntigen-Antibody ComplexAnti-Inflammatory AgentsAutoantibodiesAutophagyGynostemmaInflammationMicePlant ExtractsTOR Serine-Threonine KinasesAMP-Activated Protein KinasesAntigen-Antibody ComplexAnti-Inflammatory AgentsAutoantibodiesgypenosidePlant ExtractsSirt1 protein, mouseSirtuin 1TOR Serine-Threonine KinasesGynostemma pentaphyllum saponinsmitochondrial autophagySirt1 pathwayssystemic lupus erythematosus

Identifiers

PMID36700474
PMCPMC9275881
OpenAlexW4281885409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.