Evidence map›Paper›PMID 36700356›Full record

ArticleDevelopment and psychopathology2024

Parent-child separation and intergenerational transmission of substance use and disorder: Testing across three generations.

Austin J Blake, David P Mackinnon, Jack Waddell, Laurie Chassin

Open access · greenAbstract read
In one paragraph

Article in Development and psychopathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Austin J BlakeClinical Psychology, Arizona State University, Tempe, AZ, USA.ORCID 0000-0002-1955-6864
David P MackinnonQuantitative Psychology, Arizona State University, Tempe, AZ, USA.
Jack WaddellClinical Psychology, Arizona State University, Tempe, AZ, USA.
Laurie ChassinClinical Psychology, Arizona State University, Tempe, AZ, USA.
Arizona State University · US

Funding

Research training in substance use prevention: Closing the research-practice gapT32DA039772 · NIDA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI Cady Berkel, Nancy A. Gonzales · 2015 to 2026
$4.2M
Substance Use Among Children of AlcoholicsR01AA016213 · NIAAA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI CHASSIN, LAURIE A · 2006 to 2010
$3.1M
NIAAA NIH HHS R01 AA016213NIDA NIH HHS T32 DA039772
6 · The paper itself

Abstract

There is evidence for intergenerational transmission of substance use and disorder. However, it is unclear whether separation from a parent with substance use disorder (SUD) moderates intergenerational transmission, and no studies have tested this question across three generations. In a three-generation study of families oversampled for familial SUD, we tested whether separation between father (G1; first generation) and child (G2; second generation) moderated the effect of G1 father SUDs on G2 child SUDs. We also tested whether separation between father (G2) and child (G3; third generation) moderated the effect of G2 SUDs on G3 drinking. Finally, we tested whether G1-G2 or G2-G3 separation moderated the mediated effect of G1 SUDs on G3 drinking through G2 SUDs. G1 father-G2 child separation moderated intergenerational transmission. In families with G1-G2 separation, there were no significant effects of father SUD on G2 SUD or G3 drinking. However, in nonseparated families, greater G1 father SUDs predicted heightened G2 SUDs and G3 grandchild drinking. In nonseparated families, G1 father SUDs significantly predicted G2 SUDs, which predicted G3 drinking. However, G2-G3 separation predicted heightened G3 drinking regardless of G2 and G1 SUDs. Parental separation may introduce risk for SUDs and drinking among youth with lower familial risk.

Indexed as

ParentsSubstance-Related DisordersAdolescentHumansIntergenerational RelationsParent-Child Relationsdisorderparent-childseparationsubstanceuse

Identifiers

PMID36700356
PMCPMC10368792
OpenAlexW4318167450

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.