ArticleFrontiers in immunology2022
Systemic immune inflammation index and peripheral blood carbon dioxide concentration at admission predict poor prognosis in patients with severe traumatic brain injury.
Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 35 citations in OpenAlex.
- Pediatric Traumatic Brain Injury and Healthcare-associated Infections: A Prospective Study on Determinants of Mortality Using Least Absolute Shrinkage and Selection Operator Regression.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- Correlation of Routine Admission Inflammatory Biomarkers with Individual Traumatic Brain Lesion Types in Mild Traumatic Brain Injury.Biomedicines · 2026Article
- Intracranial pressure, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, C-reactive protein, and D-dimer mortality predictors in isolated severe traumatic brain injury.Surgical neurology international · 2026Article
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- Inflammatory mediation by neutrophil percentage to albumin ratio in the association between chronic kidney disease and presbycusis.Scientific reports · 2025Article
- The Prognostic Value of Inflammatory Indexes in Patients With Severe Traumatic Brain Injury.Brain and behavior · 2025Article
- Association between traumatic brain injury and risk of developing infections in the central nervous system and periphery.Metabolic brain disease · 2025Review
- Preoperative systemic immune-inflammation index as a superior predictor for postoperative outcomes in brain tumor patients undergoing craniotomy.Neurosurgical review · 2025Article
- An interpretable machine learning model based on optimal feature selection for identifying CT abnormalities in patients with mild traumatic brain injury.EClinicalMedicine · 2025Article
- The Association of Systemic Immune Inflammation Index (SII) and Platelet-to-Lymphocyte Ratio (PLR) on Coagulopathy and Prognosis in Patients with Traumatic Brain Injury.Journal of inflammation research · 2025Article
- Association Between Domain-Specific Physical Activity and Novel Inflammatory Biomarkers Among US Adults: Insights From NHANES 2007-2018.Mediators of inflammation · 2025Article
- Association Between Systemic Inflammation Response Index and Large Hemispheric Infarction: Development of a Predictive Diagnostic Model - A Retrospective Study.Journal of inflammation research · 2025Article
- Predicting outcomes in severe traumatic brain injury: A prospective analysis of clinical, radiological, and laboratory indicators.Surgical neurology international · 2025Article
- Prediction of Postoperative Recurrence of Chronic Subdural Hematoma Using Preoperative Systemic Immune Inflammation Index and Eosinophils.Asian journal of neurosurgery · 2024Article
- A nomogram for predicting early mortality in patients with traumatic brain injury requiring mechanical ventilation based on clinical laboratory data.Scientific reports · 2024Article
- Development and validation of a nomogram for predicting mortality in patients with acute severe traumatic brain injury: A retrospective analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Molecular subtypes and prognostic factors of lung large cell neuroendocrine carcinoma.Translational lung cancer research · 2024Article
- Neutrophil-to-lymphocyte ratio at admission for early diagnosis, severity assessment, and prognosis of acute traumatic spinal cord injury.Spinal cord · 2024Article
- Pioneering predictions of AKI and AKIN severity in burn patients: a comprehensive CBC approach.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Recent studies have shown that systemic inflammation responses and hyperventilation are associated with poor outcomes in patients with severe traumatic brain injury (TBI). The aim of this retrospective study was to investigate the relationships between the systemic immune inflammation index (SII = platelet × neutrophil/lymphocyte) and peripheral blood CO Methods: We retrospectively analyzed the clinical data for 1266 patients with severe TBI at three large medical centers from January 2016 to December 2021, and recorded the GOS 6 months after discharge. The receiver operating characteristic (ROC) curve was used to determine the best cutoff values for SII, CO Results: The ROC curves indicated that the best cutoff values of SII, CO Conclusions: SII and CO
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