ReviewPain reports2023
Factors associated with persistent postsurgical pain after total knee or hip joint replacement: a systematic review and meta-analysis.
Review in Pain reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- What proportion of people have long-term pain after total hip or knee replacement? An update of a systematic review and meta-analysis.BMJ open · 2025Pooled it
- Exercise and Pain Neuroscience Education for Patients With Chronic Pain After Total Knee Arthroplasty: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Integrating Mental Health Into Surgical Care: A Qualitative Study of a Perioperative Mental Health Intervention.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026Article
- Chronic pain after orthognathic surgery: a retrospective single-center study.Journal of oral & facial pain and headache · 2026Article
- Preoperative Surgical Fear and Association with Postoperative Pain and Quality of Recovery After Total Joint Arthroplasty.Journal of clinical medicine · 2026Article
- Observational
- Development of risk prediction model for chronic pain after knee replacement surgery: protocol for an individual patient data meta-analysis.Perioperative medicine (London, England) · 2026Article
- Associations between serum inflammatory mediators and chronic pain after laparoscopic inguinal hernia repair in elderly patients.Frontiers in human neuroscience · 2026Article
- Ipsilateral Knee Pain After Total Hip Arthroplasty: Pathogenesis and Intervention Strategies-A Narrative Review.Journal of pain research · 2026Review
- Factors Associated With the Risk of Neuropathic Pain One Year After Total Knee Arthroplasty and the Protective Role of Local Infiltration Analgesia: A Registry-Based Prospective Cohort Study.ACR open rheumatology · 2025Article
- Case Study and Literature Review: Patient-Controlled Opioid-Free Surgical Pathway for Right Total Hip Arthroplasty.Journal of orthopaedic case reports · 2025Article
- How Old is Too Old? Outcomes of Primary Total Knee Arthroplasty in Patients 70 Years or Older.Journal of orthopaedic case reports · 2025Article
- Anxiety and depression status in geriatric patients undergoing total hip arthroplasty: Correlation with postoperative pain and risk factors.World journal of psychiatry · 2025Article
- An individualized physical function improvement program for frailty elderly using goal attainment scaling (GAS) as evaluation method: protocol for a randomized controlled trial.BMC geriatrics · 2025Article
- In-Hospital Pain and Opioid Consumption After Primary Total Knee Arthroplasty Compared to Primary Total Hip Arthroplasty: Results from 7330 Patients Treated in a Fast-Track Setting.Pain and therapy · 2025Article
- Pre-operative education and prehabilitation provision for patients undergoing hip and knee replacement: a national survey of current NHS practice.BMC musculoskeletal disorders · 2025Article
- Machine learning research methods to predict postoperative pain and opioid use: a narrative review.Regional anesthesia and pain medicine · 2025Review
- Recognizing pain phenotypes: biopsychosocial sources of variability in the transition to chronic postsurgical pain.Regional anesthesia and pain medicine · 2025Review
- Presurgical anxiety and acute postsurgical pain predict worse chronic pain profiles after total knee/hip arthroplasty.Archives of orthopaedic and trauma surgery · 2025Article
- Preoperative glycaemic control, number of pain locations, structural knee damage, self-reported central sensitisation, satisfaction and personal control are predictive of 1-year postoperative pain, and change in pain from pre- to 1-year posttotal knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies have identified demographic, clinical, psychosocial, and perioperative variables associated with persistent pain after a variety of surgeries. This study aimed to perform a systematic review and meta-analysis of factors associated with persistent pain after total knee replacement (TKR) and total hip replacement (THR) surgeries. To meet the inclusion criteria, studies were required to assess variables before or at the time of surgery, include a persistent postsurgical pain (PPSP) outcome measure at least 2 months after a TKR or THR surgery, and include a statistical analysis of the effect of the risk factor(s) on the outcome measure. Outcomes from studies implementing univariate and multivariable statistical models were analyzed separately. Where possible, data from univariate analyses on the same factors were combined in a meta-analysis. Eighty-one studies involving 171,354 patients were included in the review. Because of the heterogeneity of assessment methods, only 44% of the studies allowed meaningful meta-analysis. In meta-analyses, state anxiety (but not trait anxiety) scores and higher depression scores on the Beck Depression Inventory were associated with an increased risk of PPSP after TKR. In the qualitative summary of multivariable analyses, higher preoperative pain scores were associated with PPSP after TKR or THR. This review systematically assessed factors associated with an increased risk of PPSP after TKR and THR and highlights current knowledge gaps that can be addressed by future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.