Evidence map›Paper›PMID 36699921›Full record

ReviewFrontiers in public health2022

The research progress of Chikungunya fever.

Li Cai, Xinyi Hu, Shuang Liu, Lei Wang, Hao Lu, Hua Tu, Xibao Huang, Yeqing Tong

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Bone erosions and joint damage caused by chikungunya virus: a systematic review.Revista da Sociedade Brasileira de Medicina Tropical · 2024
    Pooled it
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  19. Common arboviruses and the kidney: a review.Jornal brasileiro de nefrologia
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Li CaiDepartment of Infectious Disease Control and Prevention, Wuhan Center for Disease Control and Prevention, Wuhan, China.
Xinyi HuGlobal Study Institute, University of Geneva, Geneva, Switzerland.
Shuang LiuDepartment of Infectious Disease Control and Prevention, Hubei Center for Disease Control and Prevention, Wuhan, China.
Lei WangDepartment of Economic Management, China University of Geosciences, Wuhan, China.
Hao LuDepartment of Infectious Disease Control and Prevention, Hubei Center for Disease Control and Prevention, Wuhan, China.
Hua TuDepartment of Infectious Disease Control and Prevention, Hubei Center for Disease Control and Prevention, Wuhan, China.
Xibao HuangDepartment of Infectious Disease Control and Prevention, Hubei Center for Disease Control and Prevention, Wuhan, China.
Yeqing TongDepartment of Infectious Disease Control and Prevention, Hubei Center for Disease Control and Prevention, Wuhan, China.
Wuhan Center for Disease Control and Prevention · CNChina University of Geosciences · CNUniversity of Geneva · CHWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chikungunya fever, an acute infectious disease caused by Chikungunya virus (CHIKV), is transmitted by Aedes aegypti mosquitoes, with fever, rash, and joint pain as the main features. 1952, the first outbreak of Chikungunya fever was in Tanzania, Africa, and the virus was isolated in 1953. The epidemic has expanded from Africa to South Asia, the Indian Ocean islands and the Americas, and is now present in more than 100 countries and territories worldwide, causing approximately 1 million infections worldwide each year. In addition, fatal cases have been reported, making CHIKV a relevant public health disease. The evolution of the virus, globalization, and climate change may have contributed to the spread of CHIKV. 2005-2006 saw the most severe outbreak on Reunion Island, affecting nearly 35% of the population. Since 2005, cases of Chikungunya fever have spread mainly in tropical and subtropical regions, eventually reaching the Americas through the Caribbean island. Today, CHIKV is widely spread worldwide and is a global public health problem. In addition, the lack of a preventive vaccine and approved antiviral treatment makes CHIKV a major global health threat. In this review, we discuss the current knowledge on the pathogenesis of CHIKV, focusing on the atypical disease manifestations. We also provide an updated review of the current development of CHIKV vaccines. Overall, these aspects represent some of the most recent advances in our understanding of CHIKV pathogenesis and also provide important insights into the current development of CHIKV and potential CHIKV vaccines for current development and clinical trials.

Indexed as

Chikungunya FeverChikungunya virusAnimalsDisease OutbreaksHumansMosquito VectorsTanzaniaChikungunyaepidemiologypathogenesispreventionvaccine

Identifiers

PMID36699921
PMCPMC9870324
OpenAlexW4313909575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.