ArticleFrontiers in public health2022
Global burden of lower respiratory infections during the last three decades.
Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 4 of them syntheses that pooled it.
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Who cites it
112 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Diagnostic accuracy of point-of-care tests for acute respiratory infection: a systematic review of reviews.Health technology assessment (Winchester, England) · 2026Pooled it
- Blowing devices, resources and incentive screens during respiratory physiotherapy: a systematic review.BMC pulmonary medicine · 2025Pooled it
- Short-term and long-term effects of air pollution on acute lower respiratory infections incidence and mortality: an overview and critical appraisal of systematic reviews.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Pooled it
- Impact of improved stove intervention on infant acute respiratory infections: Results from a randomized trial in Northwest Ethiopia.PloS one · 2026Trial
- Role-specific household contact patterns in urban and rural China: Implications for influenza household transmission.Infectious Disease Modelling · 2027Article
- High Mortality in Adults With Community-Acquired Pneumonia Admitted to Hospitals in South Africa Before and During the COVID-19 Pandemic, Stratified by HIV Serostatus and Viral Load: Data From a Prospective Cohort Study (2019-2021).Open forum infectious diseases · 2026Article
- Performance evaluation of the BioFire respiratory panel 2.1 plus and exploratory analysis of Ct values for respiratory pathogen quantification.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- The Impact of Adenotonsillectomy on Respiratory Tract Infections in Pediatric Patients: A Comparative Study Using a Korean Nationwide Population-Based Cohort.Journal of rhinology : official journal of the Korean Rhinologic Society · 2026Article
- Characteristics and Risk Factors Associated With Hospitalization and Severe Disease in Patients Aged ≥ 60 Years With Human Metapneumovirus Infection Over Three Consecutive Seasons (2021-2024) in Valladolid, Spain. The VALLAVIRUS Study.Influenza and other respiratory viruses · 2026Article
- Pharmacological regulation of airway ciliary motility: endogenous mediators, pharmaceutical agents, and natural compounds with a focus on ginsenoside Rd.Journal of natural medicines · 2026Review
- Strongyloides stercoralis infection in patients presenting with lower respiratory tract infections: a retrospective case series from a tertiary hospital in Vietnam.BMC infectious diseases · 2026Article
- Delayed Radiological Resolution: A Comparative Longitudinal Study of Viral Pneumonia Evolution in Diabetic vs. Non-Diabetic Patients.Diseases (Basel, Switzerland) · 2026Article
- Wearable sensors for respiratory protection in occupational settings.Journal of safety research · 2026Review
- Changes in the burden of lower respiratory infections in China before and after the implementation of the national centralized drug procurement policy.Infectious medicine · 2026Article
- Respiratory Syncytial Virus Immunization Strategies for Older Adults in Gulf Cooperation Council Countries: Expert Consensus and Recommendations.Infectious diseases and therapy · 2026Article
- Mortality attributable to youth drinking in 194 WHO member countries/territories, 1990-2021.Scientific reports · 2026Article
- Article
- Pulmonary Function Testing Using Tidal Breath Flow-Volume Loops in Healthy Children 1-24 Months of Age in Semi-Rural Nepal: Feasibility Study.Pediatric pulmonology · 2026Article
- Article
52 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Lower respiratory infections (LRIs) cause a substantial mortality, morbidity and economic burden. The present study reported the global, regional and national burden of LRIs and their attributable risk factors in 204 countries and territories, between 1990 and 2019, by age, sex, etiology, and Socio-demographic Index (SDI). Methods: Using publicly available data from the Global Burden of Disease (GBD) study 2019, we reported the incidence, deaths and disability-adjusted life-years (DALYs), due to LRIs. Estimates were presented as counts and age-standardized rates per 100,000 population with their associated uncertainty intervals (UIs). Results: Globally, in 2019 there were 488.9 million (95% UI: 457.6 to 522.6) incident cases and 2.4 million (2.3-2.7) deaths due to LRIs. The global age-standardized incidence and death rates for LRIs were 6,295 (5,887.4-6,737.3) and 34.3 (31.1-37.9) per 100,000 in 2019, which represents a 23.9% (22.5-25.4) and 48.5% (42.9-54.0) decrease, respectively since 1990. In 2019, Guinea [12,390.4 (11,495.5-13,332.8)], Chad [12,208.1 (11,289.3-13,202.5)] and India [11,862.1 (11,087.0-12,749.0)] had the three highest age-standardized incidence rates of LRI. Equatorial Guinea [-52.7% (95% UI: -55.8 to -49.3)], Chile [-50.2% (95% UI: -53.4 to -47.0)] and Albania [-48.6% (95% UI: -51.7 to -45.3)] showed the largest decreases from 1990 to 2019. In 2019, a decrease in the incidence rate of LRI was observed at the global level up to the 25-29 age group, then the incidence rates increased with age. The burden of LRIs decreased with increasing SDI at both the regional and national levels. Globally, child wasting (33.1%), household air pollution from solid fuels (24.9%) and a lack of access to handwashing facilities (14.4%) made the largest contributions to the LRI burden in 2019. Conclusions: Although the burden of LRIs decreased over the period 1990-2019, LRIs still contribute to a large number of incident cases, deaths and DALYs. Preventative programs with a focus on reducing exposure to attributable risk factors should be implemented, especially in less developed countries.
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