Evidence map›Paper›PMID 36699807›Full record

ArticleChronic stress (Thousand Oaks, Calif.)

Dementia, Substance Misuse, and Social Determinants of Health: American Indian and Alaska Native Peoples' Prevention, Service, and Care.

Maria C Crouch, Maredyth B R Cheromiah Salazar, Steven J Harris, Rosellen M Rosich

Open access · goldAbstract read
In one paragraph

Article in Chronic stress (Thousand Oaks, Calif.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. If a Family Member Develops Alzheimer's Disease: Gender Differences in Help-Seeking Intentions Among American Indians.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Maria C CrouchDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.ORCID https://orcid.org/0000-0001-9520-5479
Maredyth B R Cheromiah SalazarDepartment of Psychology, University of Alaska Anchorage, Anchorage, AK, USA.
Steven J HarrisDepartment of Psychology, University of Pittsburgh, Pittsburgh, PA, USA.ORCID https://orcid.org/0000-0003-1217-0202
Rosellen M RosichDepartment of Psychology, University of Alaska Anchorage, Anchorage, AK, USA.
University of Alaska Anchorage · USUniversity of Pittsburgh · USYale University · US

Funding

Mentoring Emerging Scientists for Careers in Substance Use ResearchR25DA035163 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Carmen L Masson, Gideon St.Helen · 2014 to 2026
$4.6M
Secondary Analyses of Clinical Trial Data to Understand Factors Associated with Alcohol Use Among Alaska Native PopulationsF32AA029627 · NIAAA · YALE UNIVERSITY · PI CROUCH, MARIA CHRISTINA · 2021 to 2023
$215k
NIAAA NIH HHS F32 AA029627NIDA NIH HHS R25 DA035163
6 · The paper itself

Abstract

Background: American Indian and Alaska Native (AI/AN) peoples are disproportionately impacted by substance use disorders (SUDs) and health consequences in contrast to all racial/ethnic groups in the United States. This is alarming that AI/AN peoples experience significant health disparities and disease burden that are exacerbated by settler-colonial traumas expressed through prejudice, stigma, discrimination, and systemic and structural inequities. One such compounding disease for AI/AN peoples that is expected to increase but little is known is Alzheimer's disease and related dementias (ADRD). AI/AN approaches for understanding and treating disease have long been rooted in culture, context, and worldview. Thus, culturally based prevention, service, and caregiving are critical to optimal outcomes, and investigating cultural beliefs regarding ADRD can provide insights into linkages of chronic stressors, disease, prevention and treatment, and the role of substance misuse. Method: To understand the cultural practices and values that compose AI/AN Elder beliefs and perceptions of ADRD, a grounded theory, qualitative study was conducted. Twelve semistructured interviews with AI/AN Elders (M age = 73; female = 8, male = 4) assessed the etiology, course, treatment, caregiving, and the culturally derived meanings of ADRD, which provides a frame of understanding social determinants of health (SDH; eg, healthcare equity, community context) and impacts (eg, historical trauma, substance misuse) across the lifespan. Results: Qualitative analyses specific to disease etiology, barriers to treatment, and SDH revealed 6 interrelated and nested subthemes elucidating both the resilience and the chronic stressors and barriers faced by AI/AN peoples that directly impact prevention, disease progression, and related services: (1) postcolonial distress; (2) substance misuse; (3) distrust of Western medicine; (4) structural inequities; (5) walking in two worlds; and (6) decolonizing and indigenizing medicine. Conclusion: Barriers to optimal wellbeing and SDH for AI/AN peoples are understood through SUDs, ADRD, and compounding symptoms upheld by colonial traumas and postcolonial distress. En masse historical and contemporary discrimination and stress, particularly within Western medicine, both contextualizes the present and points to the ways in which the strengths, wisdom, and balance inherent in AI/AN culture are imperative to the holistic health and healing of AI/AN peoples, families, and communities.

Indexed as

American Indian/Alaska Nativedementiahistorical traumasocial determinants of healthsubstance use

Identifiers

PMID36699807
PMCPMC9869198
OpenAlexW4317387689

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.