Evidence map›Paper›PMID 36699651›Full record

ArticleERJ open research2023

Validation of a small cough detector.

Manuel Kuhn, Elif Nalbant, Dario Kohlbrenner, Mitja Alge, Laura Kuett, Alexandra Arvaji, Noriane A Sievi, Erich W Russi, Christian F Clarenbach

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Cough biomarkers for diagnosis and monitoring of respiratory disease: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
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  16. Measuring cough: what really matters?Journal of thoracic disease · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Manuel KuhnFaculty of Medicine, University of Zurich, Zurich, Switzerland.
Elif NalbantSIVA Health AG, Zurich, Switzerland.
Dario KohlbrennerDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0001-6674-5193
Mitja AlgeSIVA Health AG, Zurich, Switzerland.
Laura KuettSIVA Health AG, Zurich, Switzerland.
Alexandra ArvajiDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.
Noriane A SieviDepartment of Pulmonology, University Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0003-1758-4586
Erich W RussiFaculty of Medicine, University of Zurich, Zurich, Switzerland.
Christian F ClarenbachFaculty of Medicine, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0003-2158-2321
University Hospital of Zurich · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research question: The assessment of cough frequency in clinical practice relies predominantly on the patient's history. Currently, objective evaluation of cough is feasible with bulky equipment during a brief time ( Methods: We recorded cough epochs with SIVA-P3 over eight consecutive days in patients suffering from chronic cough. During the first 24 h, the detector was validated against cough events counted by trained human listeners. The wearing comfort and the device usage were assessed using a questionnaire. Results: In total, 27 participants (mean±sd age 50±14 years) with either chronic unexplained cough (n=12), COPD (n=4), asthma (n=5) or interstitial lung disease (n=6) were studied. During the daytime, the sensitivity of SIVA-P3 cough detection was 88.5±2.49% and the specificity was 99.97±0.01%. During the night-time, the sensitivity was 84.15±5.04% and the specificity was 99.97±0.02%. The wearing comfort and usage of the device was rated as very high by most participants. Conclusion: SIVA-P3 enables automatic continuous cough monitoring in an outpatient setting for objective assessment of cough over days and weeks. It shows comparable sensitivity or higher sensitivity than other devices with fully automatic cough counting. Thanks to its wearing comfort and the high performance for cough detection, it has the potential for being used in routine clinical practice.

Identifiers

PMID36699651
PMCPMC9868968
OpenAlexW4302307223

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.