Evidence map›Paper›PMID 36699637›Full record

ArticleJBMR plus2023

Impact of Alcohol on Bone Health in People Living With HIV: Integrating Clinical Data From Serum Bone Markers With Morphometric Analysis in a Non-Human Primate Model.

Alexandra Denys, Allison Norman, Daniel S Perrien, Larry J Suva, Liz Simon, Lee S McDaniel, Tekeda Ferguson, Kim Pedersen, David Welsh, Patricia E Molina and 1 more

Open access · goldAbstract read
In one paragraph

Article in JBMR plus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Aging Exacerbates Binge Ethanol-Mediated Bone Toxicity in Mice.Alcohol, clinical & experimental research · 2026
    Article
  4. Review
  5. Article
  6. Why Animal Experiments Are Still Indispensable in Bone Research: A Statement by the European Calcified Tissue Society.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Alexandra DenysDepartment of Pharmacology and Experimental Therapeutics Louisiana State University Health Sciences Center New Orleans LA USA.
Allison NormanDepartment of Pharmacology and Experimental Therapeutics Louisiana State University Health Sciences Center New Orleans LA USA.
Daniel S PerrienDivision of Clinical Pharmacology in the Department of Medicine Vanderbilt University Medical Center Nashville TN USA.
Larry J SuvaDepartment of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences Texas A&M University College Station TX USA.ORCID https://orcid.org/0000-0002-2892-9757
Liz SimonComprehensive Alcohol Research Center Louisiana State University Health Sciences Center New Orleans LA USA.
Lee S McDanielComprehensive Alcohol Research Center Louisiana State University Health Sciences Center New Orleans LA USA.
Tekeda FergusonComprehensive Alcohol Research Center Louisiana State University Health Sciences Center New Orleans LA USA.
Kim PedersenDepartment of Pharmacology and Experimental Therapeutics Louisiana State University Health Sciences Center New Orleans LA USA.
David WelshComprehensive Alcohol Research Center Louisiana State University Health Sciences Center New Orleans LA USA.
Patricia E MolinaComprehensive Alcohol Research Center Louisiana State University Health Sciences Center New Orleans LA USA.
Martin Jj RonisDepartment of Pharmacology and Experimental Therapeutics Louisiana State University Health Sciences Center New Orleans LA USA.ORCID https://orcid.org/0000-0002-0116-3771
Louisiana State University Health Sciences Center New Orleans · USTexas College · USVanderbilt University Medical Center · US

Funding

Translational Research/Education ComponentP60AA009803 · NIAAA · LSU HEALTH SCIENCES CENTER · PI DAVID A WELSH · 2004 to 2026
$42.6M
BIOMEDICAL ALCOHOL RESEARCH TRAINING PROGRAMT32AA007577 · NIAAA · LSU HEALTH SCIENCES CENTER · PI PATRICIA E. MOLINA · 1999 to 2026
$9.6M
The role of oxidative stress in alcohol-induced osteopeniaR37AA018282 · NIAAA · LSU HEALTH SCIENCES CENTER · PI RONIS, MARTIN J J · 2016 to 2025
$4.7M
Alcohol-Induced Bone Resorption: The Role of Oxidative StressR01AA018282 · NIAAA · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI RONIS, MARTIN J J · 2009 to 2013
$1.7M
The role of osteocytes in alcohol-induced osteopeniaF30AA028999 · NIAAA · LSU HEALTH SCIENCES CENTER · PI DENYS, ALEXANDRA · 2021 to 2023
$157k
NIAAA NIH HHS F30 AA028999NIAAA NIH HHS P60 AA009803NIAAA NIH HHS R01 AA018282NIAAA NIH HHS R37 AA018282NIAAA NIH HHS T32 AA007577
6 · The paper itself

Abstract

People living with HIV (PLWH) represent a vulnerable population to adverse musculoskeletal outcomes due to HIV infection, antiretroviral therapy (ART), and at-risk alcohol use. Developing measures to prevent skeletal degeneration in this group requires a grasp of the relationship between alcohol use and low bone mass in both the PLWH population and its constituents as defined by sex, age, and race. We examined the association of alcohol use with serum biochemical markers of bone health in a diverse cohort of PLWH enrolled in the New Orleans Alcohol Use in HIV (NOAH) study. To explore the effects of alcohol on bone in the context of HIV and ART and the role of estrogen, we conducted a parallel, translational study using simian immunodeficiency virus (SIV)

Indexed as

BIOCHEMICAL MARKERS OF BONE TURNOVERBONE MODELING AND REMODELINGDISEASES AND DISORDERS OF/RELATED TO BONENUTRITIONOSTEOPOROSIS

Identifiers

PMID36699637
PMCPMC9850440
OpenAlexW4309149112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.