Evidence map›Paper›PMID 36699622›Full record

ArticlePathology oncology research : POR2022

Angiomyolipoma of the kidney-Clinicopathological analysis of 52 cases.

Zsuzsanna Fejes, Fanni Sánta, Alex Jenei, István Előd Király, Linda Varga, Levente Kuthi

Open access · goldAbstract read
In one paragraph

Article in Pathology oncology research : POR, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zsuzsanna FejesDepartment of Radiology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.
Fanni SántaDepartment of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.
Alex JeneiDepartment of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary.
István Előd KirályDepartment of Urology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.
Linda VargaDepartment of Oncotherapy, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.
Levente KuthiDepartment of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.
University of Szeged · HUHUN-REN Institute of Experimental Medicine · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The renal angiomyolipoma (AML) is a benign tumor characteristically composed of fat, smooth muscle tissue, and vessels. We collected AMLs from our nephrectomy database, reclassified them according to their histological appearance, recorded the demographic, clinical, and pathological parameters, and compared them with oncocytoma (RO) and renal cell carcinoma (RCC). Immunohistochemistry was ordered in 41 cases. In 2224 nephrectomies, we found 52 AMLs with a 53 mm median size. The mean age was 52.76. Forty-eight tumors were sporadic, while four were hereditary. The revision resulted in 31 classic, 13 leiomyoma-like, five lipoma-like, two epithelioid, and one AML with epithelial cysts. SMA was diffusely positive, except for the epithelioid type, while MelanA harbored stronger expression than HMB45. AML was more frequent in females and appeared ten and 7 years earlier than RO and RCC, respectively. The follow-up time was 7.42 years, and neither tumor-related death nor relapse occurred. AML is rare in nephrectomies and develops primarily in females in their 50s with an average size of 50-60 mm at the surgery. The histological appearance in order of frequency is classic, leiomyoma-like, lipoma-like, epithelioid, and cystic. The MelanA, HMB45, and SMA immunohistochemistry can support the light-microscopic findings.

Indexed as

AngiomyolipomaCarcinoma, Renal CellHamartomaKidney NeoplasmsLeiomyomaLipomaAntibodies, MonoclonalFemaleHumansKidneyMART-1 AntigenMiddle AgedAntibodies, MonoclonalMART-1 AntigenAMLangiomyolipomakidney tumornephrectomytuberous sclerosis

Identifiers

PMID36699622
PMCPMC9868137
OpenAlexW4313813106

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.