ArticleFrontiers in neuroscience2022
Sensory impairment and cognitive decline among older adults: An analysis of mediation and moderation effects of loneliness.
Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Investigating the effects of reminiscence using smells on loneliness and depressive symptoms in community-dwelling older adults: a randomised controlled trial.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2025Trial
- Cognitive benefits of hearing intervention vary by risk of cognitive decline: A secondary analysis of the ACHIEVE trial.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Trial
- Sensory impairment, epigenetic ageing, and later-life functional decline and mortality in older adults.GeroScience · 2026Article
- Sensory impairment and cognitive impairment among older adults in rural China: personal responsibility for health as a possible moderator?BMC geriatrics · 2026Article
- Racial and ethnic differences in the associations of sensory impairments with cognition in older United States adults.Journal of Alzheimer's disease : JAD · 2026Article
- Sensory Deprivation and the Brain: Neurobiological Mechanisms, Psychological Effects, and Clinical Implications.Brain sciences · 2026Review
- Perception of family relationships and depressive symptoms in older adults in Loja, Ecuador: an analytical cross-sectional study.Frontiers in public health · 2026Observational
- Hearing loss and cognitive function among older adults in 18 high-income countries: Moderating and Mediating factors.Research square · 2025Article
- Review
- Visual Impairment and Cognitive Function in Aging Adults: Sex and Age Differences in Mediating Effect of Social Isolation and Depression.American journal of ophthalmology · 2025Article
- Associations of modifiable dementia risk factors with dementia and cognitive decline: evidence from three prospective cohorts.Frontiers in public health · 2025Article
- Article
- Depression, loneliness, and lower social activity as partial mediators of the association between visual impairment and cognitive decline.International journal of geriatric psychiatry · 2024Article
- Prediction Model for Cognitive Impairment among Disabled Older Adults: A Development and Validation Study.Healthcare (Basel, Switzerland) · 2024Article
- Impact of visual impairments on cognitive functions in older adults: insights from NHANES data.Frontiers in public health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Multiple studies have reported that hearing and vision impairment are linked to cognitive decline. Yet little is known about factors that may influence the association between sensory impairment and cognitive decline. This study examined if loneliness mediates or moderates the impact of sensory impairment on cognitive decline as individuals age. Methods: This was a longitudinal study using data from the Health and Retirement Study (HRS) and The Aging, Demographics, and Memory Study (ADAMS) ( Results: Loneliness moderated but did not mediate the association between visual impairment and the rate of cognitive decline (standardized β =-0.108, Conclusion: Visual impairment combined with an elevated level of loneliness may produce a more synergistic, deleterious impact on older adults' cognitive function than visual impairment alone. This study highlights the importance of promoting a healthy social and psychological status for older adults with sensory impairment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.