Evidence map›Paper›PMID 36699527›Full record

ArticleFrontiers in neuroscience2022

A transfer learning approach for multiclass classification of Alzheimer's disease using MRI images.

Rizwan Khan, Saeed Akbar, Atif Mehmood, Farah Shahid, Khushboo Munir, Naveed Ilyas, M Asif, Zhonglong Zheng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 53 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 6 countries.

Rizwan KhanDepartment of Computer Science and Mathematics, Zhejiang Normal University, Jinhua, China.
Saeed AkbarSchool of Computer Science, Huazhong University of Science and Technology, Wuhan, China.
Atif MehmoodDivision of Biomedical Imaging, Department of Biomedical Engineering and Health Systems, KTH Royal Institute of Technology, Stockholm, Sweden.
Farah ShahidDepartment of Computer Science, University of Agriculture, Sub Campus Burewala-Vehari, Faisalabad, Pakistan.
Khushboo MunirDepartment of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada.
Naveed IlyasDepartment of Physics, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates.
M AsifDepartment of Radiology, Emory Brain Health Center-Neurosurgery, School of Medicine, Emory University, Atlanta, GA, United States.
Zhonglong ZhengDepartment of Computer Science and Mathematics, Zhejiang Normal University, Jinhua, China.
Zhejiang Normal University · CNEmory University · USHuazhong University of Science and Technology · CNKhalifa University of Science and Technology · AENational University of Modern Languages · PKUniversity of Agriculture Faisalabad · PKUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's is an acute degenerative disease affecting the elderly population all over the world. The detection of disease at an early stage in the absence of a large-scale annotated dataset is crucial to the clinical treatment for the prevention and early detection of Alzheimer's disease (AD). In this study, we propose a transfer learning base approach to classify various stages of AD. The proposed model can distinguish between normal control (NC), early mild cognitive impairment (EMCI), late mild cognitive impairment (LMCI), and AD. In this regard, we apply tissue segmentation to extract the gray matter from the MRI scans obtained from the Alzheimer's Disease National Initiative (ADNI) database. We utilize this gray matter to tune the pre-trained VGG architecture while freezing the features of the ImageNet database. It is achieved through the addition of a layer with step-wise freezing of the existing blocks in the network. It not only assists transfer learning but also contributes to learning new features efficiently. Extensive experiments are conducted and results demonstrate the superiority of the proposed approach.

Indexed as

Alzheimer's diseasedeep learningearly diagnosis of ADMRImulticlass classification

Identifiers

PMID36699527
PMCPMC9869687
OpenAlexW4313985049

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.