Evidence map›Paper›PMID 36699470›Full record

ArticleFrontiers in genetics2022

DNA methylation and mRNA expression of glutathione S-transferase alpha 4 are associated with intracranial aneurysms in a gender-dependent manner.

Tianqi Xu, Xi Yu, Shenjun Zhou, Yiwen Wu, Xinpeng Deng, Yuefei Wu, Shiyi Wang, Xiang Gao, Sheng Nie, Chenhui Zhou and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Epigenetic mechanisms in aneurysm formation, growth, and rupture: A systematic review.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Review
  3. Article
  4. Review
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Tianqi XuDepartment of Neurology, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang, China.
Xi YuDepartment of Hepatopancreatobiliary Surgery, Ningbo Medical Center Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China.
Shenjun ZhouKey Laboratory of Precision Medicine for Atherosclerotic Diseases of Zhejiang Province, Ningbo, Zhejiang, China.
Yiwen WuDepartment of Neurosurgery, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang, China.
Xinpeng DengDepartment of Neurosurgery, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang, China.
Yuefei WuDepartment of Neurology, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang, China.
Shiyi WangDepartment of Neurology, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang, China.
Xiang GaoDepartment of Neurosurgery, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang, China.
Sheng NieDepartment of Neurosurgery, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang, China.
Chenhui ZhouKey Laboratory of Precision Medicine for Atherosclerotic Diseases of Zhejiang Province, Ningbo, Zhejiang, China.
Jie SunDepartment of Neurosurgery, Ningbo First Hospital, Ningbo University, Ningbo, Zhejiang, China.
Yi HuangKey Laboratory of Precision Medicine for Atherosclerotic Diseases of Zhejiang Province, Ningbo, Zhejiang, China.
Ningbo First Hospital · CNNingbo University · CNEastern Hepatobiliary Surgery Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

5-aza-2'-deoxycytidineDNA methylationglutathione S-tranferase alpha 4intracranial aneurysmmRNA expression

Identifiers

PMID36699470
PMCPMC9868450
OpenAlexW4313827496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.