Evidence map›Paper›PMID 36699324›Full record

ArticleFrontiers in veterinary science2022

Natural history of

Ali Derakhshani, Seyed Mohammad Mousavi, Masoud Rezaei, Ali Afgar, Ali Reza Keyhani, Mohammad Ali Mohammadi, Shahriar Dabiri, Majid Fasihi Harandi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. First comparative proteomic andFrontiers in veterinary science · 2025
    Article
  4. Article
  5. Article
  6. Receptor Tyrosine Kinase Signaling InvolvesTropical medicine and infectious disease · 2024
    Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ali DerakhshaniResearch Center for Hydatid Disease in Iran, Kerman University of Medical Sciences, Kerman, Iran.
Seyed Mohammad MousaviResearch Center for Hydatid Disease in Iran, Kerman University of Medical Sciences, Kerman, Iran.
Masoud RezaeiResearch Center for Hydatid Disease in Iran, Kerman University of Medical Sciences, Kerman, Iran.
Ali AfgarResearch Center for Hydatid Disease in Iran, Kerman University of Medical Sciences, Kerman, Iran.
Ali Reza KeyhaniLeishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Mohammad Ali MohammadiResearch Center for Hydatid Disease in Iran, Kerman University of Medical Sciences, Kerman, Iran.
Shahriar DabiriDepartment of Pathology, Afzalipour Medical School, Pathology and Stem Cells Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Majid Fasihi HarandiResearch Center for Hydatid Disease in Iran, Kerman University of Medical Sciences, Kerman, Iran.
Kerman University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Cystic echinococcosis (CE) caused by the cestode Methods: Results: Insulin and BMP-4 treatment of microcysts resulted in significant increase in microcyst formation, increased size, reduced apoptosis and deformation of the microcysts. Alizarin red staining of the microcysts treated with the insulin and BMP-4 confirmed that calcium deposition is significantly lower than the untreated microcysts. Also Alizarin Red staining and Immunohistochemistry of the microcysts indicates that calcium accumulation in deformed microcysts is higher than the normal ones on day 105. The microcysts began to wrinkle and the germinal layer was partially detached from the laminated layer on day 84. Conclusion: Results of the present study suggest that the degenerative changes in hydatid cysts can be slowed down by insulin and BMP-4, indicating that cellular factors and host hormones could contribute to the longevity of hydatid cysts. Significant evidences are provided suggesting that the microcysts cultivated

Indexed as

apoptosisbone morphogenetic protein (BMP)calcificationdegenerationgrowth factorhydatid disease

Identifiers

PMID36699324
PMCPMC9868913
OpenAlexW4315491136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.