ArticleTherapeutic advances in chronic disease2023
Hematological parameters and early-onset coronary artery disease: a retrospective case-control study based on 3366 participants.
Article in Therapeutic advances in chronic disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 19 citations in OpenAlex.
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- Hematological parameters and major adverse cardiovascular events: a prospective study in a Chinese population involving 2,970 participants.International journal of medical sciences · 2025Article
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- Platelet indices and the risk of pulmonary arterial hypertension: a two-sample and multivariable Mendelian randomization study.Frontiers in cardiovascular medicine · 2024Article
- The relationship between early-onset coronary artery disease and familial hypercholesterolemia: a cohort study based on the Hakka population in Meizhou, China.American journal of translational research · 2024Article
- Comment on: Hematological parameters and early-onset coronary artery disease: a retrospective case-control study based on 3366 participants.Therapeutic advances in chronic disease · 2023Article
- Author response to comment on: Hematological parameters and early-onset coronary artery disease: a retrospective case-control study based on 3366 participants.Therapeutic advances in chronic disease · 2023Article
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9 authors at 2 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Thrombosis and inflammation are crucial elements in the pathogenesis of cardiovascular disease. Hematological parameters elucidate information involving the inflammatory and blood coagulation processes. Objectives: The current study explored the association of hematological parameters with EOCAD to identify specific risk factors. Design: A single-center retrospective case-control study was conducted with 1693 coronary artery disease patients and 1693 controls. Methods: Hematological parameters were examined through an automated analyzer. Results: The basophil percentage was significantly reduced in EOCAD (0.43 ± 0.26, Conclusions: Hematological parameters are closely associated with EOCAD. Moreover, leukocyte parameters correlated with the presence and severity of the disease. In addition, erythrocyte parameters were associated with the disease presence but not with the disease severity. Among the platelet parameters, only PDW was related to the disease presence.
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