Evidence map›Paper›PMID 36699048›Full record

ReviewFrontiers in pharmacology2022

Applications for natural deep eutectic solvents in Chinese herbal medicines.

Minghui Li, Cheng Rao, Xiaoqian Ye, Mei Wang, Boyuan Yang, Chengxiao Wang, Liqun Guo, Yin Xiong, Xiuming Cui

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Sustainable Extraction ofInternational journal of molecular sciences · 2026
    Article
  6. Extraction and Identification of Active Components fromMolecules (Basel, Switzerland) · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Minghui LiFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Cheng RaoFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Xiaoqian YeFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Mei WangLeiden University-European Center for Chinese Medicine and Natural Compounds, Institute of Biology Leiden, Leiden University, Leiden, Netherlands.
Boyuan YangFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Chengxiao WangFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Liqun GuoCenter for Drug Discovery & Technology Development of Yunnan Traditional Medicine, Kunming, China.
Yin XiongFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.
Xiuming CuiFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chinese herbal medicines (CHMs), with a wide range of bioactive components, are considered to be an important source for new drug discovery. However, the process to isolate and obtain those bioactive components to develop new drugs always consumes a large amount of organic solvents with high toxicity and non-biodegradability. Natural deep eutectic solvents (NADES), a new type of green and designable solvents composed of primary plant-based metabolites, have been used as eco-friendly substitutes for traditional organic solvents in various fields. Due to the advantages of easy preparation, low production cost, low toxicity, and eco-friendliness, NADES have been also applied as extraction solvents, media, and drug delivery agents in CHMs in recent years. Besides, the special properties of NADES have been contributed to elucidating the traditional processing (also named

Indexed as

Chinese herbal medicinesextractiongreen solventNADEStraditional processing (Paozhi)

Identifiers

PMID36699048
PMCPMC9868165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.