Evidence map›Paper›PMID 36698977›Full record

ArticleComputational and structural biotechnology journal2023

Identification of crucial amino acid residues involved in large ring cyclodextrin synthesis by amylomaltase from Corynebacterium glutamicum.

Sirikul Ngawiset, Abbas Ismail, Shuichiro Murakami, Piamsook Pongsawasdi, Thanyada Rungrotmongkol, Kuakarun Krusong

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Computational and structural biotechnology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Sirikul NgawisetCenter of Excellence in Structural and Computational Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Abbas IsmailCenter of Excellence in Structural and Computational Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Shuichiro MurakamiDepartment of Agricultural Chemistry, School of Agriculture, Meiji University, Kawasaki-shi, Kanagawa 214-8571, Japan.
Piamsook PongsawasdiStarch and Cyclodextrin Research Unit, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Thanyada RungrotmongkolCenter of Excellence in Structural and Computational Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Kuakarun KrusongCenter of Excellence in Structural and Computational Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Chulalongkorn University · THMeiji University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amylomaltase can be used to synthesize large ring cyclodextrins (LR-CDs), applied as drug solubilizer, gene delivery vehicle and protein aggregation suppressor. This study aims to determine the functional amino acid positions of

Indexed as

AmylomaltaseCgAM, Corynebacterium glutamicum amylomaltaseCorynebacterium glutamicumHPAEC-PAD, High Performance Anion Exchange Chromatography with Pulsed Amperometric DetectionLarge-ring cyclodextrinLR-CDs, Large ring cyclodextrinsMD, molecular dynamicMolecular dynamic simulationRMSD, root mean square displacementSite-directed mutagenesisWT, wild type amylomaltase

Identifiers

PMID36698977
PMCPMC9860158
OpenAlexW4314935042

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.