Evidence map›Paper›PMID 36698968›Full record

ReviewComputational and structural biotechnology journal2023

Recent development of computational cluster analysis methods for single-molecule localization microscopy images.

Yoonsuk Hyun, Doory Kim

Open access · goldAbstract readReview
In one paragraph

Review in Computational and structural biotechnology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Case Study: Illuminating the Nanoscale World of Microbiology.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. SuperResNET: Model-Free Single-Molecule Network Analysis Software Achieves Molecular Resolution of Nup96.Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  10. Article
  11. Model-based evaluation of connexin hemichannel permeability.Computational and structural biotechnology journal · 2025
    Article
  12. Cluster parameter-based DBSCAN maps for image characterization.Computational and structural biotechnology journal · 2025
    Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Yoonsuk HyunDepartment of Mathematics, Inha University, Republic of Korea.
Doory KimDepartment of Chemistry, Hanyang University, Republic of Korea.
Hanyang University · KRInha University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the development of super-resolution imaging techniques, it is crucial to understand protein structure at the nanoscale in terms of clustering and organization in a cell. However, cluster analysis from single-molecule localization microscopy (SMLM) images remains challenging because the classical computational cluster analysis methods developed for conventional microscopy images do not apply to pointillism SMLM data, necessitating the development of distinct methods for cluster analysis from SMLM images. In this review, we discuss the development of computational cluster analysis methods for SMLM images by categorizing them into classical and machine-learning-based methods. Finally, we address possible future directions for machine learning-based cluster analysis methods for SMLM data.

Indexed as

Cluster analysisMachine learningSingle-molecule localization microscopySuper-resolution fluorescence microscopy

Identifiers

PMID36698968
PMCPMC9860261
OpenAlexW4313837364

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.