ArticleFrontiers in medicine2022
Case report: Kimura's disease with minimal degenerative glomerulopathy without eosinophil infiltration responds to mycophenolate mofetil treatment.
Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 8 citations in OpenAlex.
- Pruritic Plaque on the Right Lower Limb: A Rare Case of Kimura Disease and Literature Review.Clinical case reports · 2025Article
- Kimura Disease: Retrospective Analysis of 53 Cases and Three Mepolizumab-Responsive Cases.Journal of inflammation research · 2025Article
- Overlap of membranous nephropathy and IgA nephropathy in a patient with Kimura's disease: a case report and literature review.Frontiers in immunology · 2024Review
- Kimura Disease: A Detailed Analysis of Clinical and Radiological Manifestations in a Retrospective Case Series.Journal of inflammation research · 2024Article
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9 authors at 2 institutions in 1 country.
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Abstract
Kimura's disease (KD) is a rare chronic progressive immune inflammatory disease. The etiology is unknown and manifests as a chronic inflammatory process, which is more common in young Asian men. The clinical manifestations are painless subcutaneous swelling of the head and neck and periauricular lymphadenopathy, which is slow growing and has a benign course. KD may involve the kidney, and pathological examination revealed eosinophil infiltration in the renal tissue. Proteinuria has been reported in 12-16% of KD cases, and about 60-70% of KD patients will develop nephrotic proteinuria. KD is easily confused with nephrotic syndrome, because KD does not have specific clinical manifestations, laboratory and imaging, and early misdiagnosis is easy. We report a case of KD that was biopsy-proven to have minimal lesion glomerulopathy after ~11 years. In this report, we describe a clinical case of KD with nephrotic syndrome, but there's no eosinophil infiltration in the kidneys. The clinical manifestations of KD recurrence were bilateral eyelid edema, bilateral lower limb swelling, and massive proteinuria in response to mycophenolate mofetil treatment (1.5 g).
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