Evidence map›Paper›PMID 36698693›Full record

ArticleGalen medical journal2022

Neuropharmaceutical Properties of Naringin Against Alzheimer's and Parkinson's Diseases: Naringin Protection Against AD and PD.

Maryam Poudineh, Tahere Ghotbi, Farnoush Azizi, Nooshin Karami, Zahra Zolfaghari, Farshid Gheisari, Mohammad Hormozi, Sahar Poudineh

Open access · diamondAbstract read
In one paragraph

Article in Galen medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
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  5. Article
  6. Article
  7. Protective Role of an Extract Waste Product fromPlants (Basel, Switzerland) · 2023
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Maryam PoudinehSchool of Medicine, Mashhad Azad University, Mashhad, Iran.
Tahere GhotbiDepartment of Nursing, School of Nursing and Midwifery, Shiraz University of Medical Science, Shiraz, Iran.
Farnoush AziziDepartment of Nursing, School of Nursing and Midwifery, Shiraz University of Medical Science, Shiraz, Iran.
Nooshin KaramiDepartment of Clinical Psychology, Shiraz University of Education and Psychology, Shiraz, Iran.
Zahra ZolfaghariDepartment of E Learning in Medical Sciences, Virtual Faculty of Shiraz University of Medical Sciences, Shiraz, Iran.
Farshid GheisariThe Hospital for Sick Children, Toronto, Canada.
Mohammad HormoziDepartment of Neurodegenerative Diseases and Hertie, Institute for Clinical Brain Research, University of Tuebingen, 72076, Tuebingen, Germany.
Sahar PoudinehSchool of Medicine, Mashhad Azad University, Mashhad, Iran.
Islamic Azad University, Mashhad · IRShiraz University · IRHertie Institute for Clinical Brain Research · DEHospital for Sick Children · CAIranshahr University · IRShiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurological complications are considered the leading cause of disability and the second cause of death worldwide. Although the most common neurological disorders affecting a large population are Alzheimer's (AD) and Parkinson's diseases (PD), no definitive treatment has been propounded in the clinic. As in recent years, special attention has been paid to medicinal herbal products as one of the ways to meet the challenges of treating diseases. This review study aimed to introduce the naringin neuroprotective effects as an abundant flavonoid in grapes and citrus fruits on the most common neurological disorders, including AD and PD. For this purpose, the specified keywords were searched in PubMed, Web of Science, Scopus, Embase, and Google Scholar, and the results were entered into the study after a concise overview. The findings show naringin can confront neurological disorders through several mechanisms such as modulating stress response pathways, preventing apoptosis, oxidative stress, and neuroinflammation, excessive chelating amounts of metal ions, thereby improving cognitive impairment and memory loss induced by neurological disorders. However, further studies, particularly on human, are critical for the final confirmation of obtained findings. [GMJ.2022;11:e2337].

Indexed as

Alzheimer's DiseaseFlavonoidsNaringeniNaringinNeurological DisorderParkinson's Disease

Identifiers

PMID36698693
PMCPMC9838113
OpenAlexW4312932055

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.