Evidence map›Paper›PMID 36698613›Full record

ArticleHemaSphere2023

Outcome Prediction in Patients With Large B-cell Lymphoma Undergoing Chimeric Antigen Receptor T-cell Therapy.

Conrad-Amadeus Voltin, Philipp Gödel, Laura Beckmann, Jan-Michel Heger, Carsten Kobe, Nadine Kutsch, Peter Borchmann, Markus Dietlein, Ken Herrmann, Matthias Stelljes and 10 more

Open access · goldAbstract read
In one paragraph

Article in HemaSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. The prognostic utility ofFrontiers in immunology · 2024
    Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. [European journal of radiology open · 2025
    Article
  9. Metabolic Tumor Volume Response after Bridging Therapy Determines Chimeric Antigen Receptor T-Cell Outcomes in Large B-Cell Lymphoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 1 country.

Conrad-Amadeus VoltinDepartment of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany.
Philipp GödelFirst Department of Internal Medicine, Center for Integrated Oncology Aachen-Bonn-Cologne-Düsseldorf (CIO ABCD), Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany.
Laura BeckmannFirst Department of Internal Medicine, Center for Integrated Oncology Aachen-Bonn-Cologne-Düsseldorf (CIO ABCD), Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany.
Jan-Michel HegerFirst Department of Internal Medicine, Center for Integrated Oncology Aachen-Bonn-Cologne-Düsseldorf (CIO ABCD), Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany.
Carsten KobeDepartment of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany.
Nadine KutschFirst Department of Internal Medicine, Center for Integrated Oncology Aachen-Bonn-Cologne-Düsseldorf (CIO ABCD), Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany.
Peter BorchmannFirst Department of Internal Medicine, Center for Integrated Oncology Aachen-Bonn-Cologne-Düsseldorf (CIO ABCD), Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany.
Markus DietleinDepartment of Nuclear Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany.
Ken HerrmannDepartment of Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Matthias StelljesDepartment of Medicine A-Hematology, Oncology, and Pneumology, West German Cancer Center (WTZ), University Hospital Münster, University of Münster, Germany.
Kambiz RahbarDepartment of Nuclear Medicine, University Hospital Münster, University of Münster, Germany.
Georg LenzDepartment of Medicine A-Hematology, Oncology, and Pneumology, West German Cancer Center (WTZ), University Hospital Münster, University of Münster, Germany.
H Christian ReinhardtCologne Essen Lymphoma Working Group (CLWG), Cologne and Essen, Germany.
Marcel TeichertDepartment of Hematology and Stem Cell Transplantation, West German Cancer Center (WTZ), University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Richard NoppeneyDepartment of Hematology and Stem Cell Transplantation, West German Cancer Center (WTZ), University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Jörn C AlbringDepartment of Medicine A-Hematology, Oncology, and Pneumology, West German Cancer Center (WTZ), University Hospital Münster, University of Münster, Germany.
Robert SeifertDepartment of Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Bastian von TresckowCologne Essen Lymphoma Working Group (CLWG), Cologne and Essen, Germany.
Sarah FlossdorfInstitute for Medical Informatics, Biometry, and Epidemiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Christine HanounDepartment of Hematology and Stem Cell Transplantation, West German Cancer Center (WTZ), University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
University of Duisburg-Essen · DEUniversity Hospital Münster · DEHeinrich Heine University Düsseldorf · DEWest German Heart and Vascular Center Essen · DEDüsseldorf University Hospital · DEUniversity Hospital Cologne · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The introduction of chimeric antigen receptor (CAR) T-cell therapy has led to a fundamental shift in the management of relapsed and refractory large B-cell lymphoma. However, our understanding of risk factors associated with non-response is still insufficient and the search for predictive biomarkers continues. Some parameters measurable on

Identifiers

PMID36698613
PMCPMC9829285
OpenAlexW4318167781

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.