ArticleFrontiers in nutrition2022
Anti-inflammatory effects and molecular mechanisms of bioactive small molecule garlic polysaccharide.
Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
- The Anti-Constipation Effect of Garlic Polysaccharides: Roles of Gut Barrier Integrity, VIP Pathway, and the Microbiota-SCFAs Axis.Food science & nutrition · 2026Article
- Current State of Knowledge of the Anticancer Properties of Polyphenolic Compounds from Garlic (Molecules (Basel, Switzerland) · 2026Review
- Effect of Thermal Treatment on the Antiproliferative and Antioxidant Activities of Garlic.Food science & nutrition · 2025Article
- Natural products alleviate viral pneumonia by modulating inflammatory and oxidative-stress pathways.Frontiers in pharmacology · 2025Review
- A soluble garlic polysaccharide supplement alleviates fatigue in mice.NPJ science of food · 2024Article
- Water-soluble garlic polysaccharide (WSGP) improves ulcerative volitis by modulating the intestinal barrier and intestinal flora metabolites.Scientific reports · 2024Article
- Therapeutic effect of targeted antioxidant natural products.Discover nano · 2024Review
- Structural Characterization of Polygonatum Cyrtonema Polysaccharide and Its Immunomodulatory Effects on Macrophages.Molecules (Basel, Switzerland) · 2024Article
- Garlic Origin Traceability and Identification Based on Fusion of Multi-Source Heterogeneous Spectral Information.Foods (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although garlic polysaccharides have been found to possess anti-inflammatory activities, anti-inflammatory study on small molecule water-soluble garlic polysaccharide (WSGP) is few. In this study, a novel WSGP with a molecular weight of 1853 Da was isolated by DEAE-52 and Sephadex G-100 column and the chemical composition was identified by monosaccharide composition and methylation analysis. Furthermore, the antioxidant effects of WSGP and the potential molecular mechanisms on LPS-induced inflammatory responses in RAW264.7 macrophage cells were investigated. The results showed that WSGP has strong antioxidant activity, such as DPPH, hydroxyl, superoxide anion, ABTS radical scavenging capacity, Fe
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