Evidence map›Paper›PMID 36698201›Full record

ArticleTrials2023

COS-Speech: protocol to develop a core outcome set for dysarthria after stroke for use in clinical practice and research.

C Mitchell, A Bowen, P Conroy, B M Whelan, S J Wallace, A Dancer, K Woodward-Nutt, J J Kirkham

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

C MitchellSchool of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, England. claire.mitchell@manchester.ac.uk.ORCID http://orcid.org/0000-0002-2445-8468
A BowenSchool of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, England.
P ConroySchool of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, England.
B M WhelanSchool of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia.
S J WallaceSchool of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia.
A DancerCOS-Speech Healing, Empowered and Recovering from Dysarthria (HEARD) group, Manchester, UK.
K Woodward-NuttGeoffrey Jefferson Brain Research Centre, The Manchester Academic Health Science Centre, Northern Care Alliance and the University of Manchester, Manchester, UK.
J J KirkhamCentre for Biostatistics, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Manchester Academic Health Science Centre · GBThe University of Queensland · AU

Funding

Research for Patient Benefit Programme NIHR202748
6 · The paper itself

Abstract

backgroundDysarthria after stroke is when speech intelligibility is impaired, and this occurs in half of all stroke survivors. Dysarthria often leads to social isolation, poor psychological well-being and can prevent return to work and social lives. Currently, a variety of outcome measures are used in clinical research and practice when monitoring recovery for people who have dysarthria. When research studies use different measures, it is impossible to compare results from trials and delays our understanding of effective clinical treatments. The aim of this study is to develop a core outcome set (COS) to agree what aspects of speech recovery should be measured for dysarthria after stroke (COS-Speech) in research and clinical practice.

methodsThe COS-Speech study will include five steps: (1) development of a long list of possible outcome domains of speech that should be measured to guide the survey; (2) recruitment to the COS-Speech study of three key stakeholder groups in the UK and Australia: stroke survivors, communication researchers and speech and language therapists/pathologists; (3) two rounds of the Delphi survey process; (4) a consensus meeting to agree the speech outcomes to be measured and a follow-up consensus meeting to match existing instruments/measures (from parallel systematic review) to the agreed COS-Speech; (5) dissemination of COS-Speech. DISCUSSION: There is currently no COS for dysarthria after stroke for research trials or clinical practice. The findings from this research study will be a minimum COS, for use in all dysarthria research studies and clinical practice looking at post-stroke recovery of speech. These findings will be widely disseminated using professional and patient networks, research and clinical forums as well as using a variety of academic papers, videos, accessible writing such as blogs and links on social media.

trial registrationCOS-Speech is registered with the Core Outcome Measures in Effectiveness Trials (COMET) database, October 2021 https://www.comet-initiative.org/Studies/Details/1959 . In addition, "A systematic review of the psychometric properties and clinical utility of instruments measuring dysarthria after stroke" will inform the consensus meeting to match measures to COS-Speech. The protocol for the systematic reviews registered with the International Prospective Register of Systematic Reviews. PROSPERO registration number: CRD42022302998 .

Indexed as

DysarthriaSpeechDelphi TechniqueHumansOutcome Assessment, Health CareResearch DesignSystematic Reviews as TopicTreatment OutcomeCore outcome setDelphi processDysarthriaStroke

Identifiers

PMID36698201
PMCPMC9878925
OpenAlexW4318020583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.