Evidence map›Paper›PMID 36698190›Full record

ArticleJournal of nanobiotechnology2023

Tumor-penetrating nanoplatform with ultrasound "unlocking" for cascade synergistic therapy and visual feedback under hypoxia.

Zhuoyan Xie, Junrui Wang, Yuanli Luo, Bin Qiao, Weixi Jiang, Leilei Zhu, Haitao Ran, Zhigang Wang, Wei Zhu, Jianli Ren and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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  4. Article
  5. Article
  6. Ultrasound-responsive nanocarriers with siRNA and FeJournal of nanobiotechnology · 2024
    Article
  7. Review
  8. The biological roles of CD47 in ovarian cancer progression.Cancer immunology, immunotherapy : CII · 2024
    Review
  9. Intrinsic anti-inflammatory nanomedicines for enhanced pain management.Frontiers in bioengineering and biotechnology · 2024
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Zhuoyan Xie *Department of Ultrasound, Chongqing General Hospital, Chongqing, 401147, China.
Junrui Wang *Chongqing Key Laboratory of Ultrasound Molecular Imaging, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Yuanli LuoChongqing Key Laboratory of Ultrasound Molecular Imaging, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Bin QiaoChongqing Key Laboratory of Ultrasound Molecular Imaging, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Weixi JiangChongqing Key Laboratory of Ultrasound Molecular Imaging, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Leilei ZhuDepartment of Ultrasound, Chongqing General Hospital, Chongqing, 401147, China.
Haitao RanChongqing Key Laboratory of Ultrasound Molecular Imaging, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Zhigang WangChongqing Key Laboratory of Ultrasound Molecular Imaging, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Wei ZhuDepatment of Medical College, Hubei University for Nationalities, Enshi, 445000, Hubei, China. 416999645@qq.com.
Jianli RenChongqing Key Laboratory of Ultrasound Molecular Imaging, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. renjianli@cqmu.edu.cn.
Zhiyi ZhouChongqing Key Laboratory of Ultrasound Molecular Imaging, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. zzy16966@163.com.
Second Affiliated Hospital of Chongqing Medical University · CNChongqing Medical University · CNDalian Medical University · CNFirst People's Hospital of Chongqing · CNHubei University for Nationalities · CN

Funding

Basic Research and Frontier Exploration Key Project of Chongqing Science and Technology Commission Grant No. cstc2019jcyj-zdxmX0020Basic Research and Frontier Exploration Project of Yuzhong District, Chongqing 20190112Chongqing Science and Health Joint Medical Research Project Young and Middle-aged High Level Talent Project 2020GDRC011High level Medical Reserved Personnel Training Project of Chongqing, CQMU Program for Youth Innovation in Future Medicine W0026Kuanren Talents Program of the Kuanren Talents Program of the Second Affiliated Hospital of Chongqing Medical University KR2019G001National Natural Science Foundation of China Grant No.82171946Natural Science Foundation of Chongqing Grant No. cstc2020jcyj-msxmX0569
6 · The paper itself

Abstract

backgroundCombined therapy based on the effects of cascade reactions of nanoplatforms to combat specific solid tumor microenvironments is considered a cancer treatment strategy with transformative clinical value. Unfortunately, an insufficient O

resultsA visualizable nanoplatform of liposome nanoparticles loaded with GOD, H(Gd), and PFP and grafted with the peptide tLyP-1, named

conclusionWe present a visualizable nanoplatform with tumor-penetrating ability that can be unlocked by US to overcome the current treatment problems by improving the controllability of the O

Indexed as

Feedback, SensoryNanoparticlesCell Line, TumorHumansHydrogen PeroxideHypoxiaPeptidesHydrogen PeroxidePeptidesAcoustic droplet vaporizationNanoplatform-based cascade engineeringNanoultrasonic biomedicineO2 supplyTumor-penetrating peptide

Identifiers

PMID36698190
PMCPMC9878980
OpenAlexW4317952031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.