ArticleParasites & vectors2023
Plasmodium malariae contributes to high levels of malaria transmission in a forest-savannah transition area in Cameroon.
Article in Parasites & vectors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 34 citations in OpenAlex.
- Population genomics of Plasmodium malariae from 4 African countries.JCI insight · 2026Article
- Four-year monitoring of the malaria vector Anopheles funestus in central-west Cameroon reveals an escalation of pyrethroid resistance combined with high malaria transmission.BMC infectious diseases · 2026Article
- Plasmodium malariae is an overlooked malaria parasite with emerging challenges.Communications medicine · 2026Review
- Distribution of falciparum and non-falciparum malaria among symptomatic malaria patients in Dschang, West Region of Cameroon.PloS one · 2026Article
- Prevalence of Plasmodium Species Using Rapid Diagnostic Tests in Cameroon: First-Year Data From Routine Malaria Surveillance.BioMed research international · 2026Article
- Genetic polymorphism of Plasmodium falciparum using merozoite surface proteins 1 and 2 (msp-1 and msp-2) genes in Oveng and Mintom, South region of Cameroon.BMC infectious diseases · 2025Article
- Combined effect of methanolic extracts ofParasite epidemiology and control · 2025Article
- Article
- Prevalence and epidemiological characteristics of asymptomatic malaria in Sucre, Venezuela: a 2022 cross-sectional study.Malaria journal · 2025Article
- DifferentialMicrobiology spectrum · 2025Article
- Micronutrient Biomarkers and Their Association with Malaria Infection in Children in Buea Health District, Cameroon.Tropical medicine and infectious disease · 2024Article
- Histidine-rich protein (hrp) 2-based RDT false-negatives and Plasmodium falciparum hrp 2 and 3 gene deletions in low, seasonal and intense perennial transmission zones in Cameroon: a cross - sectional study.BMC infectious diseases · 2024Article
- Malaria Species Positivity Rates Among Symptomatic Individuals Across Regions of Differing Transmission Intensities in Mainland Tanzania.The Journal of infectious diseases · 2024Article
- Prevalence of non-falciparum malaria infections among asymptomatic individuals in four regions of Mainland Tanzania.Parasites & vectors · 2024Article
- Genetic diversity ofFrontiers in cellular and infection microbiology · 2024Article
- Malaria species prevalence among asymptomatic individuals in four regions of Mainland Tanzania.medRxiv : the preprint server for health sciences · 2023Article
- Geographical emergence of sulfadoxine-pyrimethamine drug resistance-associatedAntimicrobial agents and chemotherapy · 2023Article
- First Insight into Drug Resistance Genetic Markers, Glucose-6-Phosphate Dehydrogenase and Phylogenetic Patterns of Misdiagnosed Plasmodium vivax Malaria in Far North Region, Cameroon.Current microbiology · 2023Article
- Plasmodium vivax in Sub-Saharan Africa: An Advancing Threat to Malaria Elimination?The American journal of tropical medicine and hygiene · 2023Article
- Analysis of the relationship between malaria and inflammatory biomarker levels in children in rural Iraq: Impact of nutritional deficiencies, anemia, and hematological disorders.Tropical parasitologyArticle
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10 authors at 6 institutions in 7 countries.
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Abstract
backgroundMalaria control efforts are highly skewed towards Plasmodium falciparum while overlooking other Plasmodium species such as P. malariae. A better understanding of the role of Plasmodium species other than P. falciparum is needed to strengthen malaria elimination initiatives. The aim of the present study was to elucidate the contribution of P. malariae to malaria transmission in Cameroon.
methodsThe study was conducted in the Ngatti Health District, a forest-savannah transition area in the Adamawa Region, Cameroon. A total of 497 individuals aged from 1 to 85 years were diagnosed with malaria in November 2020 using a rapid diagnostic test (RDT) and microscopy. Adult mosquitoes were collected between September 2019 and March 2020 by indoor aspiration and identified morphologically and molecularly. The infection status of Plasmodium spp. was also determined by quantitative PCR, and dried blood spots were collected from 156 participants with the aim to detect different Plasmodium species by nested PCR.
resultsThe overall Plasmodium prevalence was 50.3%, 51.8% and 64.7%, as detected by microscopy, the RDT and PCR, respectively. Based on the PCR results, P. falciparum was the most prevalent species (43%); followed by co-infections P. falciparum/P. malariae (17%), P. falciparum/P. ovale (1.3%), P. falciparum/P. ovale/P. malariae (1.3%); and then by P. malariae mono-infection (2.5%). The same trend was observed using microscopy, with 35% of participants infected with P. falciparum, 11% co-infected with P. falciparum/P. malariae and 4% infected with P. malariae. The prevalence and parasite density of malaria infection varied significantly with age group (P < 0.05), with the highest prevalence rate observed in children aged 6-10 years (P = 0.0001) while the density of Plasmodium infection increased significantly in children aged < 5 years compared to the other age groups (P = 10
conclusionThe results of this study reveal the significant contribution of P. malariae, in addition to P. falciparum, to the high malaria transmission rate in this region. These findings highlight the need to deploy initiatives to also tackle this Plasmodium species to eliminate malaria in the region.
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