Evidence map›Paper›PMID 36698115›Full record

Observational studyBMC geriatrics2023

Association of loneliness and social isolation with all-cause mortality among older Mexican adults in the Mexican health and aging study: a retrospective observational study.

Ashuin Kammar-García, Ricardo Ramírez-Aldana, Paloma Roa-Rojas, Luis Raymundo Lozano-Juárez, Sergio Sánchez-García, Pamela Tella-Vega, Carmen García-Peña

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Super Movers: Epidemiology and Biology of a Novel Exceptional Aging Phenotype.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Social Isolation and Population Density: Racial and Ethnic Differences Among Older Adults.Inquiry : a journal of medical care organization, provision and financing
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ashuin Kammar-GarcíaHealth Research Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
Ricardo Ramírez-AldanaHealth Research Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
Paloma Roa-RojasHealth Research Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
Luis Raymundo Lozano-JuárezPublic Policy Laboratory, Instituto Nacional de Geriatría, Mexico City, Mexico.
Sergio Sánchez-GarcíaEpidemiological Research Unit and Health Services, Aging Area, National Medical Center XXI Century, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Pamela Tella-VegaHealth Research Division, Instituto Nacional de Geriatría, Mexico City, Mexico.
Carmen García-PeñaHealth Research Director, Instituto Nacional de Geriatría, Mexico City, Mexico. mcgarcia@inger.gob.mx.
Instituto Nacional de Pediatria · MXMexican Social Security Institute · MX

Funding

The Mexican Health and Aging Study - IIR01AG018016 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Rebeca Wong · 1999 to 2026
$22.6M
NIA NIH HHS R01 AG018016
6 · The paper itself

Abstract

backgroundPlenty of evidence shows how social isolation and loneliness are associated with increased risk for numerous diseases and mortality. But findings about their interactive or combined effects on health outcomes and mortality remains inconclusive.

objectiveAnalyze the longitudinal association of loneliness, social isolation and their interactions, with the all-cause mortality among older adults in Mexico.

methodsA retrospective observational study was conducted. Mexican adults older than 50 years were included. Data from the Mexican Health and Aging Study (MHAS) in the 2015 and 2018 waves were used. The subjects were classified according to their level of loneliness and the presence of social isolation. Multivariate logistic regression analyzes were performed to determine the degree of association between loneliness and social isolation with all-cause mortality at a 3-year follow-up.

resultsFrom the total sample of 11,713 adults aged 50 years or over, 707 (6%) did not survive, 42% presented loneliness, and 53% were classified as socially isolated. After multivariate adjustment only social isolation (OR = 1.30, 95%CI:1.03-1.64) was associated with all-cause mortality, loneliness (Mild: OR = 0.83, 95%CI:0.59-1.16; Severe: OR = 1.03, 95%CI:0.71-1.64), and the interaction between loneliness and social isolation were not associated with all-cause mortality.

conclusionSocial isolation, but not loneliness or their interaction, was associated with all-cause mortality in Mexican adults older than 50 years. This finding may help direct possible future interventions that help improve mental health in older adults from a highly collectivistic country.

Indexed as

LonelinessSocial IsolationAgedAgingHumansMexicoRetrospective StudiesLonelinessMental healthMortalityOlder adultsSocial isolation

Identifiers

PMID36698115
PMCPMC9876411
OpenAlexW4317989641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.