Evidence map›Paper›PMID 36698069›Full record

ArticleBMC ophthalmology2023

The characteristics of dome-shaped macula in Chinese children aged 4-6 years using optical coherence tomography angiography.

Lu Xiang, Yingming Zhou, Xuan Zhang, Kai Li, Chunli Fei, Yangyang Wang, Yang Bai, Bing Xie, Xi Shen

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Visual and refractive outcomes up to 5 years of age of dome-shaped macula detected by handheld spectral domain optical coherence tomography in preterm infants.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2025
    Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Lu Xiang *Department of Ophthalmology, Ruijin Hospital, Shanghai Jiaotong University of Medicine, No,197, Ruijin 2nd Road, Huangpu District, Shanghai, China.
Yingming Zhou *Department of Ophthalmology, Ruijin Hospital, Shanghai Jiaotong University of Medicine, No,197, Ruijin 2nd Road, Huangpu District, Shanghai, China.
Xuan ZhangDepartment of Ophthalmology, Wuxi Branch of Ruijin Hospital, Shanghai Jiaotong University of Medicine, Shanghai, China.
Kai LiDepartment of Ophthalmology, Wuxi Branch of Ruijin Hospital, Shanghai Jiaotong University of Medicine, Shanghai, China.
Chunli FeiDepartment of Ophthalmology, Wuxi Branch of Ruijin Hospital, Shanghai Jiaotong University of Medicine, Shanghai, China.
Yangyang WangDepartment of Ophthalmology, Wuxi Branch of Ruijin Hospital, Shanghai Jiaotong University of Medicine, Shanghai, China.
Yang BaiDepartment of Ophthalmology, Wuxi Branch of Ruijin Hospital, Shanghai Jiaotong University of Medicine, Shanghai, China.
Bing Xie *Department of Ophthalmology, Ruijin Hospital, Shanghai Jiaotong University of Medicine, No,197, Ruijin 2nd Road, Huangpu District, Shanghai, China. brinkleybing@126.com.
Xi Shen *Department of Ophthalmology, Ruijin Hospital, Shanghai Jiaotong University of Medicine, No,197, Ruijin 2nd Road, Huangpu District, Shanghai, China. carl_shen2005@126.com.
Ruijin Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the characteristics of dome-shaped macula (DSM) in children aged 4-6 years with normal visual acuity using optical coherence tomography angiography.

methodThis is a cross-sectional study. A total of 19 children aged 4-6 years were included. The results of optical coherence tomography angiography images were analysed to identify and quantify retinal structural and vascular parameters in DSM children. The dome height, dome base, and sub-dome choroidal thickness were manually measured. Participants with DSM and those without DSM from our previous study were compared on these parameters.

resultsNineteen eyes of the preschool subjects with normal visual acuity showed horizontal DSM on optical coherence tomography (OCT). The DSM was significantly smooth and low in the children, and we did not observe differences between sex and age. Compared to the children without DSM, the average axial length was longer, and the average macular vessel density was lower in the DSM group, especially in the deep retinal vascular density. Additionally, the dome height was positively correlated with the sub-dome choroidal thickness. When the dome base/height was increased, the fovea avascular zone (FAZ) area was larger.

conclusionDome-shaped macula was detected in the preschool children in the process of the emmetropization with normal visual acuity. The changes in macular structure and vasculature provide new ideas for further investigation into the characteristics of DSM formation.

Indexed as

Macula LuteaTomography, Optical CoherenceChild, PreschoolCross-Sectional StudiesEast Asian PeopleFluorescein AngiographyHumansRetrospective StudiesVisual AcuityChineseDome-shaped maculaOptical coherence tomography angiographyPreschool children

Identifiers

PMID36698069
PMCPMC9878753
OpenAlexW4317937559

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.