Evidence map›Paper›PMID 36698034›Full record

ArticleJournal of endocrinological investigation2023

The Italian Society of Andrology and Sexual Medicine (SIAMS), along with ten other Italian Scientific Societies, guidelines on the diagnosis and management of erectile dysfunction.

G Corona, D Cucinotta, G Di Lorenzo, A Ferlin, V A Giagulli, L Gnessi, A M Isidori, M I Maiorino, P Miserendino, A Murrone and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of endocrinological investigation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

G CoronaEndocrinology Unit, Medical Department, Maggiore-Bellaria Hospital, Azienda Usl, Bologna, Italy.
D CucinottaChair of Internal Medicine, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
G Di LorenzoSection of Psychiatry, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
A FerlinUnit of Andrology and Reproductive Medicine, Department of Medicine, University of Padova, Padua, Italy.
V A GiagulliInterdisciplinary Department of Medicine-Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, University of Bari "Aldo Moro", Bari, Italy.
L GnessiSection of Food Science, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
A M IsidoriSection of Endocrinology, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
M I MaiorinoDivision of Endocrinology and Metabolic Diseases, Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy.
P MiserendinoDiabetology and Endocrinology Unit, ASP #, Caltanissetta, Italy.
A MurroneCardiology Unit, Città di Castello and Gubbio-GualdoTadino Hospitals, Azienda Usl Umbria 1, Gubbio, Italy.
R PivonelloDipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Unità di Andrologia e Medicina della Riproduzione e della Sessualità Maschile e Femminile, Università Federico II di Napoli, Naples, Italy.
V RochiraDepartment of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
G M SangiorgiDepartment of Biomedicine and Prevention, Policlinico Tor Vergata, Rome, Italy.
G StagnoDiabetology Unit, ASP Reggio Calabria, Reggio Calabria, Italy.
C ForestaUnit of Andrology and Reproductive Medicine, Department of Medicine, University of Padova, Padua, Italy.
A LenziSection of Food Science, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
M MaggiEndocrinology Unit, Department of Experimental, Clinical and Biomedical Sciences, University of Florence, Florence, Italy.
E A JanniniChair of Endocrinology and Sexual Medicine (ENDOSEX), Department of Systems Medicine, University of Rome Tor Vergata, E Tower South Floor 4, Room E413, Via Montpellier 1, 00133, Rome, Italy. eajannini@gmail.com.ORCID http://orcid.org/0000-0002-5874-039X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeErectile dysfunction (ED) is one of the most prevalent male sexual dysfunctions. ED has been in the past mistakenly considered a purely psycho-sexological symptom by patients and doctors. However, an ever-growing body of evidence supporting the role of several organic factors in the pathophysiological mechanisms underlying ED has been recognized.

methodsThe Italian Society of Andrology and Sexual Medicine (SIAMS) commissioned an expert task force involving several other National Societies to provide an updated guideline on the diagnosis and management of ED. Derived recommendations were based on the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system.

resultsSeveral evidence-based statements were released providing the necessary up-to-date guidance in the context of ED with organic and psychosexual comorbidities. Many of them were related to incorrect lifestyle habits suggesting how to associate pharmacotherapies and counseling, in a couple-centered approach. Having the oral therapy with phosphodiesterase type 5 inhibitors as the gold standard along with several other medical and surgical therapies, new therapeutic or controversial options were also discussed.

conclusionsThese are the first guidelines based on a multidisciplinary approach that involves the most important Societies related to the field of sexual medicine. This fruitful discussion allowed for a general agreement on several recommendations and suggestions to be reached, which can support all stakeholders in improving couple sexual satisfaction and overall general health.

Indexed as

AndrologyErectile DysfunctionCounselingHumansMaleSexual BehaviorSocieties, ScientificErectile dysfunctionObesityPhosphodiesterase type 5 inhibitorsPremature ejaculationSexual desireTestosterone

Identifiers

PMID36698034
PMCPMC9876440

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.