Evidence map›Paper›PMID 36697828›Full record

ArticleNature2023

Visualization of translation and protein biogenesis at the ER membrane.

Max Gemmer, Marten L Chaillet, Joyce van Loenhout, Rodrigo Cuevas Arenas, Dimitrios Vismpas, Mariska Gröllers-Mulderij, Fujiet A Koh, Pascal Albanese, Richard A Scheltema, Stuart C Howes and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed
26.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 172 citations in OpenAlex.

  1. Visualization of membrane-stabilized SorCS2Journal of structural biology: X · 2026
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  8. eLife · 2026
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42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Max GemmerStructural Biochemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands.
Marten L ChailletStructural Biochemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands.ORCID http://orcid.org/0000-0001-7231-7742
Joyce van LoenhoutStructural Biochemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands.
Rodrigo Cuevas ArenasStructural Biochemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands.ORCID http://orcid.org/0000-0002-2354-1286
Dimitrios VismpasStructural Biochemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands.
Mariska Gröllers-MulderijStructural Biochemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands.
Fujiet A KohThermo Fisher Scientific, Eindhoven, The Netherlands.
Pascal AlbaneseBiomolecular Mass Spectrometry and Proteomics Group, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.
Richard A ScheltemaBiomolecular Mass Spectrometry and Proteomics Group, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.ORCID http://orcid.org/0000-0002-1668-0253
Stuart C HowesStructural Biochemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands.
Abhay KotechaThermo Fisher Scientific, Eindhoven, The Netherlands.ORCID http://orcid.org/0000-0002-4480-5439
Juliette FedryStructural Biochemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands. j.m.m.fedry@uu.nl.ORCID http://orcid.org/0000-0002-6592-4269
Friedrich FörsterStructural Biochemistry, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands. f.g.forster@uu.nl.ORCID http://orcid.org/0000-0002-6044-2746
Utrecht University · NLThermo Fisher Scientific (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dynamic ribosome-translocon complex, which resides at the endoplasmic reticulum (ER) membrane, produces a major fraction of the human proteome

Indexed as

Endoplasmic ReticulumIntracellular MembranesProtein BiosynthesisCalcium-Binding ProteinsGuanosine TriphosphateHumansMembrane GlycoproteinsMembrane ProteinsMultiprotein ComplexesPeptide Elongation Factor 1Protein Sorting SignalsProtein TransportReceptors, Cytoplasmic and NuclearReceptors, PeptideRibosomesRNA, MessengerCalcium-Binding ProteinsGuanosine TriphosphateMembrane GlycoproteinsMembrane ProteinsMultiprotein ComplexesPeptide Elongation Factor 1Protein Sorting SignalsReceptors, Cytoplasmic and NuclearReceptors, PeptideRNA, MessengerSEC Translocation Channelssignal sequence receptor

Identifiers

PMID36697828
PMCPMC9892003
OpenAlexW4317952826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.