ArticleNature2023
Tissue CD14
Open access · greenAbstract read
In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
11.2field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 68 citations in OpenAlex.
- Review
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- Spatially defined danger zone shapes gastric cancer progression through CCDC80Apoptosis : an international journal on programmed cell death · 2026Article
- Liver metastases dampen IL18-driven γδ T cell activity and immunotherapy responsiveness in colorectal cancer.Cell reports. Medicine · 2026Article
- TNF-⍺-mediated myeloid-instructed CD14Cell reports. Medicine · 2026Article
- The double-positive cells in the tumor microenvironment.Journal of translational internal medicine · 2026Article
- Gut metabolites: key factors in the cross-talk between the gut microbiota and tumor immunotherapy.Frontiers in immunology · 2026Review
- Spatial niche remodeling of senescent liver-resident immune cells and its role in chronic liver diseases.Frontiers in medicine · 2026Review
- Methyl-CpG-binding domain protein 2 epigenetically represses monocyte HLA-DR expression and promotes immune paralysis in HBV-related acute-on-chronic liver failure.Frontiers in immunology · 2026Article
- Neutrophil membrane-coated nanoparticles for targeted therapy.Discover nano · 2025Review
- Engineered nano-bacteria hybrids for precision cancer immunotherapy.Materials today. Bio · 2025Review
- Tissue-resident memory CD8Nature reviews. Gastroenterology & hepatology · 2025Review
- Blood-borne immune cells carry low biomass DNA remnants of microbes in patients with colorectal cancer or inflammatory bowel disease.Gut microbes · 2025Article
- Article
- scKAN: interpretable single-cell analysis for cell-type-specific gene discovery and drug repurposing via Kolmogorov-Arnold networks.Genome biology · 2025Article
- Article
- Dissecting the mechanisms of MASLD fibrosis in the era of single-cell and spatial omics.The Journal of clinical investigation · 2025Review
- The dual nature of TFEBS letters · 2025Review
- Regulatory role of gut microbiota in immunotherapy of hepatocellular carcinoma.Hepatology international · 2025Review
- A novel approach to cancer rehabilitation: assessing the influence of exercise intervention on postoperative recovery and survival rates.International journal of surgery (London, England) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
43 authors at 8 institutions in 4 countries.
Laura J PallettDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK. laura.pallett@ucl.ac.uk.ORCID http://orcid.org/0000-0002-4161-9462
Leo SwadlingDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.ORCID http://orcid.org/0000-0002-0537-6715
Mariana DinizDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
Alexander A MainiDivision of Medicine, University College London, London, UK.
Marius SchwabenlandInstitute of Neuropathology, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0003-2205-5427
Adrià Dalmau GasullInstitute of Neuropathology, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0002-8410-8048
Jessica DaviesDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
Stephanie KucykowiczDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.ORCID http://orcid.org/0000-0002-8849-218X
Jessica K SkeltonDepartment of Medicine, Imperial College London, London, UK.
Niclas ThomasDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
Nathalie M SchmidtDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.ORCID http://orcid.org/0000-0002-9841-8418
Oliver E AminDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
Upkar S GillBlizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Kerstin A StegmannDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
Alice R BurtonDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
Emily StephensonBiosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Gary ReynoldsBiosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Matt WhelanDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.ORCID http://orcid.org/0000-0003-0441-3358
Jenifer SanchezSchool of Immunology and Microbial Sciences, Kings College London, London, UK.
Roel de MaeyerDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.ORCID http://orcid.org/0000-0003-4041-0867
Clare ThakkerDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
Kornelija SuveizdyteDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
Imran UddinDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.ORCID http://orcid.org/0000-0003-0736-3149
Ana M Ortega-PrietoDepartment of Medicine, Imperial College London, London, UK.ORCID http://orcid.org/0000-0002-9023-0103
Charlotte GrantDivision of Surgery, University College London, London, UK.
Farid FroghiDivision of Surgery, University College London, London, UK.
Giuseppe FusaiDivision of Surgery, University College London, London, UK.
Sabela LensDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.
Sofia Pérez-Del-PulgarLiver Unit, Hospital Clinic, IDIBAPS and CIBEREHD, University of Barcelona, Barcelona, Spain.ORCID http://orcid.org/0000-0002-9890-300X
Walid Al-AkkadInstitute for Liver & Digestive Health, University College London, London, UK.
Giuseppe MazzaInstitute for Liver & Digestive Health, University College London, London, UK.
Mahdad NoursadeghiDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.ORCID http://orcid.org/0000-0002-4774-0853
Arne AkbarDivision of Medicine, University College London, London, UK.ORCID http://orcid.org/0000-0002-3763-9380
Patrick T F KennedyBlizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Brian R DavidsonDivision of Surgery, University College London, London, UK.
Marco PrinzInstitute of Neuropathology, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0002-0349-1955
Benjamin M ChainDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.ORCID http://orcid.org/0000-0002-7417-3970
Muzlifah HaniffaBiosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.ORCID http://orcid.org/0000-0002-3927-2084
Derek W GilroyDivision of Medicine, University College London, London, UK.ORCID http://orcid.org/0000-0003-3476-0844
Marcus DornerDepartment of Medicine, Imperial College London, London, UK.ORCID http://orcid.org/0000-0003-0321-4226
Bertram Bengsch *Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0003-2552-740X
Anna Schurich *Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.ORCID http://orcid.org/0000-0002-2525-3114
Mala K MainiDivision of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK. m.maini@ucl.ac.uk.ORCID http://orcid.org/0000-0001-6384-1462
University College London · GBUniversity of Freiburg · DEImperial College London · GBNewcastle University · GBCentro de Investigación Biomédica en Red · ESInstitute of Infection and Immunity · CAKing's College London · GBQueen Mary University of London · GB
Funding
Cancer Research UK 26603Cancer Research UK 26813Medical Research Council G0801213Medical Research Council G0901374MRF_ MRF-044-0001-RG-SWADLMRF_ MRF-044-0004-F-GILL-C0823Wellcome Trust
Abstract
The liver is bathed in bacterial products, including lipopolysaccharide transported from the intestinal portal vasculature, but maintains a state of tolerance that is exploited by persistent pathogens and tumours
Indexed as
CD8-Positive T-LymphocytesImmune ToleranceLipopolysaccharide ReceptorsLipopolysaccharidesLiverMyeloid CellsBacteriaChemokine CXCL12Chemotaxis, LeukocyteHumansInterleukin-10Interleukin-2IntestinesNeoplasmsReceptors, Antigen, T-CellCD14 protein, humanChemokine CXCL12CXCL12 protein, humanIL10 protein, humanInterleukin-10Interleukin-2Lipopolysaccharide ReceptorsLipopolysaccharidesReceptors, Antigen, T-Cell
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.