Evidence map›Paper›PMID 36697824›Full record

ArticleNature2023

Structural basis of Rho-dependent transcription termination.

Vadim Molodtsov, Chengyuan Wang, Emre Firlar, Jason T Kaelber, Richard H Ebright

Open access · greenAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
18.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 89 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
  5. Article
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  7. Article
  8. Structural basis of long-range transcription-translation coupling.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Article
  10. Review
  11. ARNA (New York, N.Y.) · 2026
    Article
  12. Article
  13. Article
  14. Genome-wide strand-specific UV mutagenesis inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vadim Molodtsov *Waksman Institute and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, USA.ORCID http://orcid.org/0000-0003-3002-4794
Chengyuan Wang *Waksman Institute and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, USA. cywang@ips.ac.cn.ORCID http://orcid.org/0000-0002-8605-0716
Emre FirlarRutgers CryoEM and Nanoimaging Facility and Institute for Quantitative Biomedicine, Rutgers University, Piscataway, NJ, USA.
Jason T KaelberRutgers CryoEM and Nanoimaging Facility and Institute for Quantitative Biomedicine, Rutgers University, Piscataway, NJ, USA.ORCID http://orcid.org/0000-0001-9426-1030
Richard H EbrightWaksman Institute and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, USA. ebright@waksman.rutgers.edu.ORCID http://orcid.org/0000-0001-8915-7140
Rutgers, The State University of New Jersey · US

Funding

The Stanford-SLAC CryoEM Center supplementU24GM129541 · NIGMS · STANFORD UNIVERSITY · PI CHIU, WAH, HEDMAN, BRITT · 2018 to 2023
$54.8M
NCCAT: National Center for CryoEM Access and Training- Supplement for Windows 10 and FFIU24GM129539 · NIGMS · NEW YORK STRUCTURAL BIOLOGY CENTER · PI DE MARCO, ALEX, KIEFT, JEFFREY S · 2018 to 2023
$53.9M
TRANSCRIPTION ACTIVATION BY CAPR01GM041376 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI RICHARD H. EBRIGHT · 1989 to 2026
$6.5M
BACTERIAL TRANSCRIPTION COMPLEXESR37GM041376 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI EBRIGHT, RICHARD H. · 2013 to 2022
$5.0M
NIGMS NIH HHS R01 GM041376NIGMS NIH HHS R37 GM041376NIGMS NIH HHS U24 GM129539NIGMS NIH HHS U24 GM129541
6 · The paper itself

Abstract

Rho is a ring-shaped hexameric ATP-dependent molecular motor. Together with the transcription elongation factor NusG, Rho mediates factor-dependent transcription termination and transcription-translation-coupling quality control in Escherichia coli

Indexed as

Escherichia coliEscherichia coli ProteinsTranscription FactorsTranscription Termination, GeneticAdenosine TriphosphateCryoelectron MicroscopyDNA-Directed RNA PolymerasesPeptide Elongation FactorsRNAAdenosine TriphosphateDNA-Directed RNA PolymerasesEscherichia coli ProteinsNusG protein, E coliPeptide Elongation FactorsRho protein, E coliRNATranscription Factors

Identifiers

PMID36697824
PMCPMC9911385
OpenAlexW4317952730

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.