ArticleCommunications chemistry2022
Sample illumination device facilitates in situ light-coupled NMR spectroscopy without fibre optics.
Article in Communications chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Continuous-Wave (CW) Photo-CIDNP NMR Spectroscopy: A Tutorial.Magnetic resonance in chemistry : MRC · 2025Article
- One-Vat Multimaterial 3D Printing: The Devil is in the Details.ACS central science · 2025Review
- Predictions of Steady-State Photo-CIDNP Enhancement by Machine Learning.Journal of the American Chemical Society · 2025Article
- Photo-CIDNP for quantification of micromolar analytes in urine.Communications chemistry · 2025Article
- In Situ Light-driven pH Modulation for NMR Studies.Angewandte Chemie (International ed. in English) · 2025Article
- Bis-Cycloruthenated Complexes in Visible Light-Induced C-H Alkylation with Epoxides.Journal of the American Chemical Society · 2025Article
- Fast Pure Shift NMR Spectroscopy Using Attention-Assisted Deep Neural Network.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Assessing Photostability of mAb Formulations In Situ Using Light-Coupled NMR Spectroscopy.Analytical chemistry · 2024Article
- Photochemistry of Ru(II) Triazole Complexes with 6-Membered Chelate Ligands: Detection and Reactivity of Ligand-Loss Intermediates.Inorganic chemistry · 2024Article
- Hyperpolarization-Enhanced NMR Spectroscopy of Unaltered Biofluids Using Photo-CIDNP.Analytical chemistry · 2024Article
- Light-coupled cryogenic probes to detect low-micromolar samples and allow for an automated NMR platform.Magnetic resonance (Gottingen, Germany) · 2024Article
- Increased Free Radical Generation during the Interaction of a Quinone-Quinoline Chelator with Metal Ions and the Enhancing Effect of Light.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Multinuclear 1D and 2D NMR withNature communications · 2023Article
- Ultrafast Fragment Screening Using Photo-Hyperpolarized (CIDNP) NMR.Journal of the American Chemical Society · 2023Article
- Facile Detection of Light-Controlled Radical Scavengers from Natural Products Using In Situ UV-LED NMR Spectroscopy.Antioxidants (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
In situ illumination of liquid-state nuclear magnetic resonance (NMR) samples makes it possible for a wide range of light-dependent chemical and biological phenomena to be studied by the powerful analytical technique. However, the position of an NMR sample deep within the bore of the spectrometer magnet renders such illumination challenging. Here, we demonstrate the working principles of a sample illumination device (NMRtorch) where a lighthead containing an LED array is positioned directly at the top of an NMRtorch tube which is inserted into the NMR spectrometer. The wall of the tube itself acts as a light guide, illuminating the sample from the outside. We explore how this new setup performs in a number of photo-NMR applications, including photoisomerisation and photo-chemically induced dynamic nuclear polarisation (photo-CIDNP), and demonstrate the potential for ultraviolet (UV) degradation studies with continuous online NMR assessment. This setup enables users of any typical liquid-state spectrometer to easily perform in situ photo-NMR experiments, using a wide range of wavelengths.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.